Tohoku University · 공학
아츠시 스즈끼 교수의 연구실은 근육 섬유 유형의 구조적 이질성과 생물학적 기능 간의 관계를 조직화학적·생물역학적 방법으로 탐구합니다. 특히 가금류 및 반추류의 골격근에서 myofibrillar ATPase의 pH 안정성에 기반한 근섬유 유형 분류와 그 기능적 특성에 대한 연구를 중심으로, 근육의 기능적 분할과 운동 기능 간의 연관성을 규명하고자 합니다. 또한, 근육의 생리적 특성과 기능적 분화를 이해하기 위한 기초 연구를 지속적으로 수행하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
The composition of myofiber types varies within thigh muscles of chickens. The present study was designed to determine whether or not myofiber types were distributed uniformly across the diameter of the thigh muscles of chickens. Cross sections from middle portions of muscles were used histochemically to examine differences in distribution and composition of myofiber types in the muscles. Myofibers that reacted moderately (M) or strongly (S) for myosin adenosine triphosphatase (ATPase) after pre
In general, a steel beam is assembled with a concrete slab using shear connectors. Recently, perfobond-shear connectors have been attracting interest because of their high shear stiffness and strength. Nevertheless, the mechanical behavior and performance of perfobond-shear connectors under a reversed cyclic stress remain unclear. For this study, cyclic loading tests were conducted on the component model of a composite beam possessing different configurations of perfobond-shear connectors, diffe
In the design of steel structures, composite effects of stud shear connectors are generally measured using ordinary push-out tests. Furthermore, based on those results, the evaluation formulas of the ultimate shear strength are given in design guidelines. However, a concrete slab is subjected to reversed stress during an earthquake, whereas existing tests consider only compressive stresses on concrete. The mechanical behavior in existing structures thereby might be different from that under comp
The m. supraspinatus has the compartmentalized, deep, and caudal regions occupied by SO myofibers, which seem to be specialized for maintenance of the joint extension. The medial region of the m. infraspinatus may assist in the joint stabilization.
メン羊と牛の骨格筋の筋線維型におけるmyofibrillar ATPaseのpH安定性を組織化学的に調べた.クリオスタット切片をATPaseの反応の前に,酸およびアルカリの溶液に浸漬することにより,これらの動物のA型とB型筋線維のmyofibrillar ATPaseは,酸不安定•アルカリ安定性であり,C型,D型,E型筋線維のそれは,酸安定•アルカリ不安定性であることがわかった.pH 4.0の前処理で,D型筋線維のATPase活性は,C型およびE型筋線維よりも強く抑制された.酸およびアルカリ安定性のA型筋線維が見つかったが,その数は少なく,個々の筋肉および個体ではないものもあった.室温(16～18°C)でpH 4.3の前処理後のATPase反応では,めん羊と牛の間でpHに対する感受性のわずかな差が,ある種の筋肉のB型筋線維でみられた.酸およびアルカリ前処理における温度は,このATPase活性の抑制に影響を及ぼすことが示された.
A buckling-restrained braced frame (BRBF) reduces the response of buildings during a strong earthquake, during which the surrounding members such as beams and columns must resist the axial force imposed by the buckling-restrained braces (BRBs). However, the steel beams and columns are subjected to reversed axial force from the horizontal and vertical component of BRB axial force. The steel beams might then buckle under the compressive force or even yield under the subsequent tensile axial force
Buckling-restrained braced frames (BRBFs) are attracting interest worldwide by virtue of their extraordinary response reduction performance. The system relies strongly on the energy dissipation of buckling-restrained braces (BRBs). Therefore, the surrounding members (beams, columns, or gusset plates) must sustain the force imposed by a BRB. Notably, beams are not designed primarily to support the axial force. The sections consequently tend to become deep and slender to enhance the flexural stren
The presence of subtypes of dark and light myofibers distinguished by myosin adenosine triphosphatase (ATPase) reaction after alkaline preincubation was studied in thigh muscles of chickens. The dark myofibers were subclassified into type II and SS, and the light myofibers into type I, SM, and MM myofibers by the pH sensitivity of myosin ATPase. Type I myofibers reacted strongly for acid-stable ATPase and weakly for alkali-stable ATPase. Type II myofibers reacted negatively for acid-stable ATPas
The longissimus muscle of common dolphins (Delphinus delphis) was examined by histochemical methods. The longissimus muscle had two types of myofibers: types I and II. Type I myofibers possessed strong acid-stable myosin adenosine triphosphatase (ATPase) and weak alkali-stable ATPase activity, very strong activity of NADH: Nitro BT oxidoreductase (NADHOX), and strong activity of sn-glycerol-3-phosphate: menadione oxidoreductase (GPOX). Type II myofibers possessed weak acid-stable ATPase and stro
