Dong Hui Lim
성균관대학교 안과 · 의학
Dong Hui Lim 교수의 연구실은 주로 안과학 및 신경과학 분야에서 시력 이상과 신경퇴행성 질환 간의 연관성, 특히 시각 기능 이상이 파킨슨병이나 치매와 같은 신경질환의 조기 징후로 작용할 수 있다는 점을 중심으로 연구를 진행하고 있습니다. 또한 천연 식물 추출물(예: 데일비스클로우, 인디안 건초열매)의 통증 완화 효과를 동물 모델을 통해 평가하며, 안과적 질환, 특히 건성 안구의 생체지표와 관련된 생리학적 기전을 규명하고자 합니다. 이 연구들은 임상적 적용 가능성이 높은 생물학적 기전 탐색을 목표로 하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
The present study was conducted to investigate the effect of parental refractive errors on myopic children in Korean families using a nationally representative survey. We used the ophthalmologic examination dataset of the Korean National Health and Nutrition Examination Surveys IV and V, a nationwide population-based cross-sectional study using a complex, stratified, multistage, probability cluster survey, which were performed from 2008-2012. We included 3,862 children from 5-18 years of age fro
Recent studies suggested that an association exists between vision loss and cognitive impairment, although it is still vague whether there are causal relationships or direct association between low vision and dementia. We were to investigate the association between low vision and dementia in the Korean population using the National Health Insurance Service (NHIS) database. We analyzed the data of 6,029,657 subjects aged ≥40 years, drawn from Korea National Health Insurance Service. The hazard ra
Harpagophytum procumbens, also known as Devil's Claw, has historically been used to treat a wide range of conditions, including pain and arthritis. The study was designed to investigate whether H. procumbens extracts exhibit analgesic effects in plantar incision and spared nerve injury (SNI) rats. The whole procedure was performed on male SD rats. To evaluate pain-related behavior, we performed the mechanical withdrawal threshold (MWT) test measured by von Frey filaments. Pain-related behavior w
Low visual acuity was associated with the development of PD. This suggests that visual dysfunction is one of the premotor symptoms for PD development. © 2020 International Parkinson and Movement Disorder Society.
Indian gooseberry (<i>Emblica officinalis</i> fruit), also known as "Amla" is one of the oldest edible fruits known in India. It has also traditionally been used to treat inflammation, and as an analgesic to treat wounds. However, experimental evidence for the analgesic effects of <i>E. officinalis</i> has been lacking. The present study investigated whether <i>E. officinalis</i> extracts exhibit analgesic effects in the plantar incision (PI) and spared nerve injury (SNI) pain-model rats. We eva
This retrospective comparative study was to evaluate tear osmolarity measured by I-Pen osmolarity system (I-MED Pharma Inc, Dollard-des-Ormeaux, Quebec, Canada) in healthy subjects without dry eye disease (DED) and patients with DED, and its association with other ocular surface parameters. This study comprised 65 eyes of 65 patients. The ocular surface parameters including tear osmolarity with I-Pen osmometer of the patients who visited the refractive surgery center of Samsung Medical Center be
LASIK using the VisuMax femtosecond laser supplied good clinical results and flap reproducibility in both the 80- and 120-μm flap groups. Patients with relatively thin cornea may benefit from 80-μm flap LASIK.
Eleutherococcus senticosus (Siberian ginseng), has been used as a powerful tonic herb with an impressive range of health benefits. This medicinal herb has been commonly used to treat bone metabolism diseases due to its traditional Korean medicine use to strengthen muscle and bone. This study was conducted to investigate prevention of bone loss by a standardized extract of dried E. senticosus stem bark in an ovariectomized (OVX) rat model of osteoporosis. The OVX groups were divided into five gro
In the present study, we examined the ameliorating effects of demethoxycurcumin (DMC) on memory impairment induced by scopolamine using passive avoidance and Morris water maze tests in mice. Moreover, to determine the neurobiological effects underlying the ameliorating effects of the DMC, choline acetyltransferase (ChAT) immunoreactivity was evaluated in mice exposed to scopolamine. Our results demonstrated that chronic oral administration (28 days) of DMC (10 mg/kg) improved scopolamine-induced
Among the factors analyzed, small pupil size and short axial length predicted good near vision after phacoemulsification and monofocal IOL implantation.
NCT04411615.
There was a significantly higher incidence of IOL dislocation among young males, even though the higher incidence of cataract surgery was observed among older females. These estimates of the nationwide, population-based incidence of IOL dislocation can help increase understanding of the population vulnerable to IOL dislocation.