Dong Il Park
성균관대학교 의과대학 · 의학
Dong Il Park 교수의 연구실은 대장암 및 위장관계 질환의 조기 진단과 비침습적 스크리닝 기법 개발에 초점을 맞추고 있습니다. 특히 qFIT, 에피제네틱 마커, 그리고 저잔여식이식 등 혁신적인 진단 방법과 치료 전략을 연구하며, 환자의 부담을 줄이고 진료의 정밀도를 높이는 데 기여하고 있습니다. 장내에서의 유전자 메틸화 변화나 체중 지표와의 연관성 등 메타볼로믹스와 임상 내 endoscopy의 융합 연구도 진행 중입니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
The qFIT provides a higher sensitivity for detecting ACRN and cancer than the GT, and has an acceptable specificity that significantly reduces the need for colonoscopic evaluation in the screened population.
CT-P13 appears to have comparable efficacy, safety, and interchangeability with its originator in the treatment of IBD. Further prospective studies with long-term follow-up periods will be needed to confirm the biosimilarity of CT-P13.
These results suggest that a diagnosis of high-grade dysplasia in forceps biopsy material should be considered an absolute indication for ESP or EMR.
Abstract Background: The relationship between obesity and gastroesophageal reflux disease (GERD) is controversial. The aim of the present study was to investigate the potential roles of body mass index (BMI) and waist circumference on GERD in a Korean population. Methods: A total of 2457 subjects who visited the Kangbuk Samsung Hospital medical screening center for esophagogastroduodenoscopy from September 2004 to April 2005 were enrolled. All participants were given a questionnaire to determine
Our results have demonstrated that the promoter hypermethylation for methylguanine DNA methyltransferase, human Mut L homolog-1, and vimentin in stool samples is a feasible epigenetic marker that is a sensitive, specific, and noninvasive alternative for colorectal cancer screening. This method of screening for colorectal cancer may be useful for patients that decline screening because of fear or inconvenience.
A prepackaged low residue one-day diet provided cleansing efficacy similar to that of a clear liquid diet and offered the benefit of improved tolerability compared to the conventional PEG 4L regimen.