Eun‐Seok Park
성균관대학교 약학대학 · 약학
Eun-Seok Park 교수의 연구실은 주로 의약품의 약물용해도 향상, 전달 시스템 최적화, 그리고 신약 후보 물질의 기전 규명을 중심으로 연구를 진행하고 있습니다. 특히 리튬이온 배터리의 전해질 용매 개발과 같은 에너지 저장 소재 연구도 함께 수행하며, 약물의 생체 이용률을 높이기 위한 나노코팅, 코ating, 코 crystallization 기술에 초점을 맞추고 있습니다. 또한 식물 유래 천연물의 탈모 치료 효과나 항혈전 작용 메커니즘 등 생물학적 기전 규명에도 기여하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
1,2-Dimethoxyethane (DME) has been widely used as an electrolyte solvent for lithium metal batteries on account of its intrinsic reductive stability; however, its low oxidative stability presents a major challenge for use in high-voltage Li metal batteries (LMBs). In this direction, herein, we introduce a new low-dielectric solvent, 1,2-dimethoxypropane (DMP), as an electrolyte solvent. Compared to DME, DMP has decreased solvation power owing to its increased steric effects, thus promoting anion
A solid dispersion of rebamipide was successfully formulated using the spray-drying method. Bioavailability and efficacy of rebamipide were increased significantly by solubility enhancement of the drug.
<i>Centipeda minima</i> (L.) A. Braun & Asch is a well-studied plant in Chinese medicine that is used for the treatment of several diseases. A recent study has revealed the effects of extract of <i>Cetipeda minima</i> (CMX) standardized by brevilin A in inducing hair growth. However, the mechanism of action of CMX in human hair follicle dermal papilla cells (HFDPCs) has not yet been identified. We aimed to investigate the molecular basis underlying the effect of CMX on hair growth in HFDPCs. CMX