大阪大学 · Medicine
히로야수 이소 교수의 연구실은 심혈관 질환과 만성질환의 예방을 중심으로 한 영양 및 생활습관 요법에 초점을 맞추고 있습니다. 고지혈증과 뇌출혈, 심장병 간의 연관성, 오메가-3 지방산 및 어류 섭취의 심혈관 보호 효과, 카페인 섭취와 당뇨병 위험, 수면 시간과 전반적인 사망률 간의 U자형 관계 등 다양한 생활습관 요인이 건강에 미치는 영향을 체계적으로 연구하고 있습니다. 특히 식이요법, 미네랄 섭취, 항산화 물질의 역할에 대한 기초 및 인구역학적 연구를 통해 예방의학의 실질적 적용 방안을 모색하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
We examined the relation between the serum total cholesterol level and the risk of death from stroke during six years of follow-up in 350,977 men, 35 to 57 years of age, who had no history of heart attack and were not currently being treated for diabetes mellitus. The diagnosis of stroke and the type of stroke were obtained from death certificates. Using proportional-hazards regression to control for age, cigarette smoking, diastolic blood pressure, and race or ethnic group, we found that the si
Compared with a modest fish intake of once a week or &20 g/d, a higher intake was associated with substantially reduced risk of coronary heart disease, primarily nonfatal cardiac events, among middle-aged persons.
Our data indicate that higher consumption of fish and omega-3 polyunsaturated fatty acids is associated with a reduced risk of thrombotic infarction, primarily among women who do not take aspirin regularly, but is not related to risk of hemorrhagic stroke.
Consumption of green tea, coffee, and total caffeine was associated with a reduced risk for type 2 diabetes.
Both short and long sleep duration were associated with increased mortality from cardiovascular disease, noncardiovascular disease/noncancer, and all causes for both sexes, yielding a U-shaped relationship with total mortality with a nadir at 7 hours of sleep.
Low calcium intake, and perhaps low potassium intake, may contribute to increased risk of ischemic stroke in middle-aged American women. It remains possible that women in the lowest quintile of calcium intake had unknown characteristics that made them susceptible to ischemic stroke.
Perceived mental stress was associated with increased mortality from stroke for women and with CHD for men and women.
A higher intake of linoleic acid may protect against ischemic stroke, possibly through potential mechanisms of decreased blood pressure, reduced platelet aggregation, and enhanced deformability of erythrocyte cells.
UK Medical Research Council, British Heart Foundation, Cancer Research UK, European Union BIOMED programme, and National Institute on Aging (US National Institutes of Health).
