Kyoto University · 의학
히로유키 후지모토 교수의 연구실은 고온 초전도체의 기계적 안정성 향상과 산업적 응용 가능성을 연구하고 있습니다. 특히 MPMG 공정으로 제작된 YBCO 및 REBCO 초전도체의 균열 및 파손 거칠기 메커니즘을 분석하며, 211 상의 분산이 초전도체의 내구성에 미치는 영향을 규명하고 있습니다. 또한 리튬이온 배터리의 그래파이트 음극에서의 리튬 인터칼레이션 거치의 기초 반응 메커니즘을 실시간 X선 회절 분석과 결합해 정밀하게 분석하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
The fracture toughness of melt-powder-melt-growth(MPMG)-processed YBaCuO samples was measured and the beneficial effect of the dispersed 211 particles in the 123 superconducting phase on toughening the material was confirmed. Preferred fracture planes were (100), (010) and (001) planes, and the fracture toughness of the (001) plane was lower than that of the (100) and (010) planes.
Mechanical properties, such as flexural strength, fracture toughness and ductility, and superconducting properties, Tc, Jc and Hirr, are crucial for industrial applications of high-Tc oxide superconductors. However, oxide superconductors have the intrinsic brittleness of the perovskite structure, thus the strength and the fracture toughness of the materials are low and anisotropic. Therefore, it is very important to study and improve mechanical properties to achieve structural reliability for ap
Since the commercialization of rechargeable Li ion batteries in the early 1990 s, the performance of these devices has continually improved. In such batteries, graphite is typically used as the negative electrode and the present work examined the reaction mechanisms at graphite negative electrodes based on operando synchrotron X-ray diffraction analyses during charge/discharge. The resulting in-plane diffraction patterns of the Li-intercalated graphite permitted a detailed analysis of changes in
The emergence of small interfering RNA (siRNA) opened a new opportunity to study gene functions in a genome. However, large-scale loss-of-function analyses further require cell-based high-throughput methods that allow simultaneous silencing of the huge number of genes by siRNA. In this study, we aim at fabricating the cell-based siRNA arrays that facilitate parallel introduction of multiple siRNAs into cultured mammalian cells. The siRNA arrays were prepared using surface chemical processes incl
Pancreatic β-cell mass (BCM) has a central importance in the pathophysiology of diabetes mellitus. Recently, pancreatic β-cell-specific imaging, especially positron emission tomography (PET) with exendin-based probes, has emerged for non-invasive evaluation of BCM. We developed a novel exendin-based probe labeled with fluorine-18, [<sup>18</sup>F]FB(ePEG12)12-exendin-4 (<sup>18</sup>F-Ex4) for PET imaging. We subsequently conducted a first-in-human phase 1 study of <sup>18</sup>F-Ex4 PET/compute