Hokyou Lee
연세대학교 의과대학 · 의학
Hokyou Lee 교수의 연구실은 고혈압, 심혈관질환, 대사질환 및 간질환 간의 상관관계를 중심으로 한 전인적 심혈관 건강 연구를 수행하고 있습니다. 특히 청소년기 및 청년층의 혈압 분류가 심혈관 위험에 미치는 영향, 저소득 및 약물 순응도가 심혈관 결과에 미치는 영향, 간지방증과 간섬유화가 대장암 및 심장 기능 이상과 연결되는 메커니즘을 다룹니다. 대규모 국가 보험 데이터를 기반으로 한 장기 추적 연구를 통해 임상적 실천에 기여할 수 있는 정밀 위험 분류 및 예방 전략을 개발하고자 합니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Among young adults, stage 1 ISH, IDH, and SDH were all associated with higher CVD risks than normal BP. The CVD risks of stage 1 ISH and IDH were similar to each other but lower than the risk of stage 1 SDH. Categorizing young adults with stage 1 hypertension further into stage 1 ISH, IDH, and SDH may improve risk stratification for identifying high-risk individuals.
Background Low socioeconomic status and poor medication adherence are known to be associated with increased morbidity and mortality among patients with hypertension, but their combined effects have not been studied. We therefore evaluated the joint association of household income and medication adherence with death and cardiovascular disease in patients newly treated for hypertension. Methods and Results This was a nationwide cohort study using the Korean National Health Insurance database. We i
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FLD was associated with a higher risk of CRC development. CRC risk was higher in the presence of MAFLD, especially when accompanied by liver fibrosis.
Liver fibrosis was associated with LV diastolic dysfunction in patients with T2DM and may be an independent risk factor for diastolic dysfunction, especially in patients without systemic insulin resistance.
title: Associations of Ideal Cardiovascular Health and Its Change During Young Adulthood With Premature Cardiovascular Events: A Nationwide Cohort Study, doi: 10.1161/CIRCULATIONAHA.121.054212, category: Article
title: Cardiovascular Risk of Isolated Diastolic Hypertension Defined by the 2017 American College of Cardiology/American Heart Association Blood Pressure Guideline: A Nationwide Age-Stratified Cohort Study, doi: 10.1161/HYPERTENSIONAHA.120.16018, category: Article
The 2017 American College of Cardiology/American Heart Association (ACC/AHA) high blood pressure (BP) guideline lowered the cut-off for hypertension, but its age-specific association with cardiovascular disease (CVD) remains inconclusive in different populations. We evaluated the association between high BP according to the 2017 ACC/AHA guideline and CVD risks in Koreans aged 20-94 years. In a nationwide health screening cohort, we included 15,508,537 persons aged 20-94 years without prior CVD.
Regional difference in hypertension management was evident in the past, but has become less apparent over the last 15 years in Korea.
