Hwang Gyun Jeon
성균관대학교 의예과 · 의학
황균전 교수의 연구실은 우수한 수술적 결과를 위한 혁신적 수술 기구 개발과 함께, 신장세포암과 신장기증 환자의 기능적 예후를 예측하고 최적화하는 데 초점을 맞추고 있습니다. 단일구멍로 시행하는 복강경 수술의 효율성 향상과 맞물려, 신장 기능 예측을 위한 전술적 영상 측정법 및 체형 지표 분석도 활발히 진행되고 있습니다. 특히 비만 지표와 체내 지방 분포가 신장세포암 환자의 병리적 특성과 예후에 미치는 영향에 대한 독창적 연구로 국내외에서 주목받고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Our homemade single port device is cost-effective, provides adequate range of motion and is more flexible in port placement for laparoendoscopic single site surgery than the current multichannel port.
Renal mass biopsy for a small renal mass can be performed accurately. Nondiagnostic renal mass biopsy was common for smaller masses and cystic masses, and during the initial years of the study. A second biopsy should be considered in nondiagnostic biopsy cases.
Preoperative kidney volume is an independent predictor of GFR in RCC patients who underwent radical or partial nephrectomy.
Kidney volume measured by the voxel count method was accurate and correlated with kidney function. Preoperative kidney volume is an independent predictor of the volume increase and delayed kidney function recovery in donors that could be used clinically.
Our findings suggest that overweight and obese Korean patients with renal cell carcinoma have more favorable pathological features and a better prognosis than those with a normal body mass index.
High visceral fat area might represent a predictor of better prognosis in patients with advanced renal cell carcinomas undergoing nephrectomy.
In this series, PNI was associated with established parameters of biologically aggressive disease, and was an important prognostic factor for biochemical failure-free survival in patients undergoing radical prostatectomy. This finding supports routine evaluation of the PNI status in radical prostatectomy specimens and suggests that patients with PNI should be more closely followed after surgery.
RTV was correlated with PTV and pathologic grade. RTV was larger than the PTV for a tumor size 7 cm or less or in clear cell RCC. RTV may be useful to measure tumor burden preoperatively.
Findings suggest that the prognostic significance of perirenal fat invasion depends on primary tumor size. Perirenal fat invasion included in the pT3a stage regardless of tumor size should be reevaluated by tumor size for a more accurate patient prognosis.
Results show that trichostatin A may synergistically enhance gemcitabine mediated cell cycle arrest and apoptosis, suggesting the potential of using histone deacetylase inhibitors as combination agents to enhance the antitumor effect of gemcitabine for advanced bladder cancer.