Hyoung‐Il Kim
연세대학교 의과대학 · 의학
이 교수의 연구실은 위암 치료의 예후 예측 및 치료 전략 개선을 목표로 하며, 영양 및 면역 상태 평가 지표인 PNI의 임상적 의미를 규명하고 있습니다. 특히 위암 환자의 수술 후 예후와 관련된 면역-영양 지표의 역할, 병행 수술 방법의 영향, 그리고 철분 대사 이상의 메커니즘을 중심으로 기초와 임상 연구를 융합한 연구를 수행하고 있습니다. 또한, 췌장 이식의 최적 이식 부위 선정에 관한 실험적 연구를 통해 이식 성공률 향상 전략을 모색하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
To evaluate the predictive and prognostic significance of the prognostic nutritional index (PNI) in a large cohort of gastric cancer patients who underwent gastrectomy.Assessing a patient's immune and nutritional status, PNI has been reported as a predictive marker for surgical outcomes in various types of cancer.We retrospectively reviewed data from a prospectively maintained database of 7781 gastric cancer patients who underwent gastrectomy from January 2001 to December 2010 at a single center
ClinicalTrials.gov Identifier: NCT02892643.
Although the liver is the most common site for pancreatic islet transplantation, it is not optimal. We compared kidney, liver, muscle, and omentum as transplantation sites with regard to operative feasibility, and the efficiency of implantation and glycemic control. Islets from C57BL/6 mice were transplanted into diabetic syngeneic recipients. The mean operative time and mortality were measured to assess feasibility. To assess implantation efficiency, the marginal mass required to cure diabetes
NCT01283893.
Iron deficiency occurs in most patients with gastric cancer after gastrectomy, and its incidence was different according to the extent of gastrectomy and reconstruction method. To improve iron metabolism after distal gastrectomy, gastroduodenostomy would be the method of reconstruction whenever possible.
A higher regulatory T cells/helper T cells ratio is associated with an unfavorable prognosis and loco-regional recurrence pattern in gastric cardia cancer.
Multivariate analysis using total IEQ and IEQ/g as outcome variables indicated that age older than 2, being male and moderate distension by Liberase injection are major determinants influencing successful islet isolation.
