Hyuk‐Soo Han
서울대학교 의예과 · 의학
한 교수의 연구실은 주로 고령 환자를 중심으로 한 고관절 및 무릎 치환술의 장기적 임상 결과와 합병증, 특히 무산성 이완의 원인을 분석하는 데 초점을 맞추고 있습니다. 특히 고혈당 조절 불량이 퇴행성 관절염 환자의 수술 후 합병증에 미치는 영향이나, 전향적 골수 내 고정술을 통한 골절 치유 등 정형외과 수술의 기술적 최적화를 연구하고 있습니다. 영상 기반의 해부학적 축 분석을 통해 후방 경사도 측정 오차를 최소화하는 데도 기여하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
We have examined the results obtained with 72 NexGen legacy posterior stabilised-flex fixed total knee replacements in 47 patients implanted by a single surgeon between March 2003 and September 2004. Aseptic loosening of the femoral component was found in 27 (38%) of the replacements at a mean follow-up of 32 months (30 to 48) and 15 knees (21%) required revision at a mean of 23 months (11 to 45). We compared the radiologically-loose and revised knees with those which had remained well-fixed to
Level III Therapeutic study.
Poorly controlled hyperglycemia before surgery may increase the incidence of wound complications among diabetic patients after TKA.
Abstract The authors aimed to demonstrate the relationship between the sagittal mechanical axis of the tibia and other reference axes of the tibia and fibula in patients with advanced osteoarthritis of the knee joints, and then to identify a reliable landmark in order to minimize posterior tibial slope measurement errors. We evaluated 133 osteoarthritic knees with neutral or varus deformity in 64 female and 8 male patients. Axial computed tomographic images of whole tibiae including knee and ank
With retrograde intramedullary nailing, excellent fracture union and good functional recovery were obtained in patients with periprosthetic supracondylar fractures.
IV.
The validity and reliability of the Musculoskeletal Tumor Society functional evaluation system were evaluated using the Nottingham Health Profile, the Short Form-36, and the EuroQol protocol to measure the quality of life of patients with malignant musculoskeletal tumors. Forty-nine patients were assessed and osteosarcoma around the knee was the most common type of tumor. Prosthetic reconstructions had been done in 55.1% of patients. In a content validity analysis, neither social nor psychologic
Overall midterm high-flexion TKA survival in our Asian cohort was lower than that of conventional and other high-flexion designs. This unusually high rate of femoral component loosening was associated with postoperative high-flexion activities.
III.
We undertook this study to characterize changes in the proliferative capacities, chondrogenic phenotypes, and gene expression profiles of human synovium-derived progenitor cells from osteoarthritic patients during in vitro expansion. Cells isolated from osteoarthritic synovia were cultured, and growth rates during serial passages were evaluated. Surface molecule expressions were determined by flow cytometry and cytogenetic analyses were performed. After chondrogenic differentiation in cell pelle
This study aimed to evaluate growth factor concentration in platelet-rich plasma (PRP) (leukocyte-rich PRP) based on storage temperature, duration of storage, and method of activation. PRP samples were stored at 24℃ (room temperature group), 4℃ (refrigerator group), and -70℃ (deep-freezer group). In each temperature, four aliquots were prepared based on the time of analysis (immediately, 1, 3, and 7 days after preparation). After storage, concentrations of platelet-derived growth factor-AA (PDGF