서울대학교 · Medicine
김형진 교수의 연구실은 영상의학 및 병리학 기반의 정밀의료를 목표로 하며, 특히 흉부 영상(CT, MRI)을 활용한 폐암 및 감염성 질환(예: COVID-19)의 조기 진단과 예후 예측에 중점을 두고 있습니다. 레지오너믹스, 딥러닝 기반 영상 특징 추출, 영상 품질 최적화 기술을 통해 임상적 유용성을 높이는 연구를 진행하고 있습니다. 특히, 고해상도 영상 분석과 데이터 기반 모델링을 통해 환자 맞춤형 진료 지원 체계를 구축하고자 합니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Background Recent studies have suggested that chest CT scans could be used as a primary screening or diagnostic tool for coronavirus disease 2019 (COVID-19) in epidemic areas. Purpose To perform a meta-analysis to evaluate diagnostic performance measures, including predictive values of chest CT and initial reverse transcriptase polymerase chain reaction (RT-PCR). Materials and Methods Medline and Embase were searched from January 1, 2020, to April 3, 2020, for studies on COVID-19 that reported t
Most of the radiomic features were significantly affected by the reconstruction algorithms. Inter-reconstruction algorithm variability was greater than inter-reader variability for entropy, homogeneity, and GLCM-based features.
Background Deep learning models have the potential for lung cancer prognostication, but model output as an independent prognostic factor must be validated with clinical risk factors. Purpose To develop and validate a preoperative CT-based deep learning model for predicting disease-free survival in patients with lung adenocarcinoma. Materials and Methods In this retrospective study, a deep learning model was trained to extract prognostic information from preoperative CT examinations. Data set 1 f
Mass measurement of GGNs showed measurement variability from -17.7% to 18.6% and may be a useful method in the follow-up of GGNs with solid portions less than or equal to 5 mm.
Pulmonary subsolid nodules (SSNs) refer to pulmonary nodules with pure ground-glass nodules and part-solid ground-glass nodules. SSNs are frequently encountered in the clinical setting, such as screening chest computed tomography (CT). The main concern regarding pulmonary SSNs, particularly when they are persistent, has been lung adenocarcinoma and its precursors. The CT manifestations of SSNs help radiologists and clinicians manage these lesions. However, the management plan for SSNs has not pr
Reduced FOV DWI of the pancreas provides better overall IQ including better anatomic detail, lesion conspicuity and subjective clinical utility.
BackgroundPathologic visceral pleural invasion (pVPI) leads to upstaging from T1 to T2. However, it is unclear whether the CT features for pVPI can be reliably used as a clinical T2 descriptor for preoperative staging.PurposeTo validate the diagnostic accuracy and analyze the prognostic value of CT findings for the prediction of pVPI in patients with resected node-negative lung adenocarcinoma.Materials and MethodsThis retrospective cohort study included clinical T1N0M0 adenocarcinomas resected b
Background Low-dose CT screening for lung cancer in a tuberculosis-endemic country may be less effective because of false-positive results caused by tuberculosis sequelae. Purpose To evaluate the impact of tuberculosis sequelae at CT screening according to the American College of Radiology Lung CT Screening Reporting and Data System (Lung-RADS) using data from the Korean Lung Cancer Screening Project (K-LUCAS). Materials and Methods This is a secondary analysis of K-LUCAS (ClinicalTrials.gov ide
Tumor diameter has traditionally been used as a standard metric in terms of diagnosis and prognosis prediction of lung cancer. However, recent advances in imaging techniques and data analyses have enabled novel quantitative imaging biomarkers that can characterize disease status more comprehensively and/or predict tumor behavior more precisely. The most widely used imaging modality for lung tumor assessment is computed tomography. Therefore, we focused on computed tomography imaging biomarkers s
Cumulative histogram analysis of nCBV using 3 T MRI can be a useful method for preoperative glioma grading. The nCBV C99 value is helpful in distinguishing high- from low-grade gliomas and grade IV from III gliomas.
