서울대학교 · 의학
Hyung-Min Kwon 교수의 연구실은 피부 재생 및 신경질환 분야에서의 세포외소포와 대사 상태 간의 연관성을 중심으로 연구를 진행하고 있습니다. 특히 지방줄기세포에서 유래한 엑소좀을 활용한 비세포 치료 전략과 당화지수, 인슐린저항성 지표 등 대사적 요인이 피부질환 및 뇌질환에 미치는 영향을 규명하고자 합니다. 임상적 적용 가능성이 높은 혈액 생물학적 마커를 기반으로 한 질병의 조기 진단 및 예방 전략 개발에도 주력하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
A variety of applications of human adipose tissue stem cell-derived exosomes have been suggested as novel cell-free therapeutic strategies in the regenerative and aesthetic medical fields. This study evaluated the clinical efficacy and safety of adipose tissue stem cell-derived exosomes as an adjuvant therapy after application of fractional CO2 laser for acne scars. A 12-week prospective, double-blind, randomized, split-face trial was performed. A total of 25 patients received 3 consecutive trea
Patients with acute stroke with elevated serum homocysteine levels are at an increased risk for END.
Recent studies have suggested that dietary factors, specifically glycaemic load, may be involved in the pathogenesis of acne. The aim of this study was to determine the clinical and histological effects on acne lesions of a low glycaemic load diet. A total of 32 patients with mild to moderate acne were randomly assigned to either a low glycaemic load diet or a control group diet, and completed a 10-week, parallel dietary intervention trial. Results indicate successful lowering of the glycaemic l
MetS was found to be significantly associated with SBI. This finding has clinical utility in terms of identifying healthy people at increased risk of developing SBI.
A high TyG index was associated with a higher prevalence and burden of cSVD in a neurologically healthy population. This marker of IR could be a convenient and useful predictor of cSVD.
clinicaltrials.gov Identifier: NCT00576693.
An optimized therapeutic regimen involving a non-ablative fractionated laser or radiofrequency therapy for acne scars has not yet been established. To evaluate whether the combination of a non-ablative fractional laser (NAF) and fractional micro-needling radiofrequency (FMR) has clinical advantages for the treatment of atrophic acne scars compared with NAF alone, a 16-week prospective, randomized split-face study was performed. Each facial side of a patient was treated with 3 sessions of either
Cerebral SVD is associated with recurrent stroke in patients with LAA. Additionally, it may affect any mechanisms of recurrent stroke and even with a dose response manner.
Ectasia of the BA other than elongation or angulation appears to contribute to the occurrence of PPI. These findings may be helpful in predicting certain types of stroke.
Awareness of stroke, depression, and BP was enhanced when using the smartphone-based mHealth system. Emerging mHealth techniques have potential as new nonpharmacological secondary prevention methods because of their ubiquitous access, near real-time responsiveness, and comparatively lower cost.