박현욱 교수

We have proposed a reconstruction method using machine learning to accelerate imaging time, which reconstructs high-quality images from subsampled k-space data. It shows flexibility in the use of k-space sampling patterns, and can reconstruct images in real time.

The discrete wavelet transform (DWT) has several advantages of multiresolution analysis and subband decomposition, which has been successfully used in image processing. However, the shift-variant property is intrinsic due to the decimation process of the wavelet transform, and it makes the wavelet-domain motion estimation and compensation inefficient. To overcome the shift-variant property, a low-band-shift method is proposed and a motion estimation and compensation method in the wavelet-domain

Active contours or snakes are an effective edge-based method in segmenting an object of interest. However, the segmented boundary of a moving object in one video frame may lie far from the same moving object in the next frame due to its rapid motion, causing the snake to converge on the wrong edges. To guide the snake toward the appropriate edges, we have added gradient directional information to the external image force to create a "directional snake." Thus, in minimizing the snake energy, the

Semisolid magnetization transfer contrast (MTC) and chemical exchange saturation transfer (CEST) MRI based on MT phenomenon have shown potential to evaluate brain development, neurological, psychiatric, and neurodegenerative diseases. However, a qualitative MT ratio (MTR) metric commonly used in conventional MTC imaging is limited in the assessment of quantitative semisolid macromolecular proton exchange rates and concentrations. In addition, CEST signals measured by MTR asymmetry analysis are u

Magnetization transfer contrast MR fingerprinting (MTC-MRF) is a novel quantitative imaging method that simultaneously quantifies free bulk water and semisolid macromolecule parameters using pseudo-randomized scan parameters. To improve acquisition efficiency and reconstruction accuracy, the optimization of MRF sequence design has been of recent interest in the MRF field, but has been challenging due to the large number of degrees of freedom to be optimized in the sequence. Herein, we propose a

The proposed CNN could obtain water-fat-separated images from the multi-echo images acquired from the bipolar multi-echo gradient-recalled echo sequence, which included artifacts from the bipolar gradients.

Metal artifacts in the MR image were drastically corrected by the proposed unsupervised learning method. Two distorted images obtained with dual-polarity readout gradients are used as the input of the deep neural network. The proposed method can train networks without labels and does not overfit the network, even with small training data sets.

Utilizing a speedup operator, the proposed method reduced the evolution time. Robust and accurate results for various datasets were obtained in experiments.

The suggested registration method can be applied to any MR images for functional studies. It can also be applied to patients unless their brains are highly deformed or have a highly deformed CC.

The proposed method is an end-to-end MR image reconstruction method based on recurrent neural networks. It performs direct mapping of the input k-space data and the reconstructed images, operating as a unified solution that is applicable to various scanning trajectories.

The proposed scheme can simultaneously optimize b-values and train DNN to minimize quantification errors of IVIM parameters. The trained DNN can quantify IVIM parameters from the diffusion-weighted images obtained with the optimized b-values.

The only-train-once deep-learning framework can improve the reconstruction accuracy of brain-tissue parameter maps and be further combined with any conventional MRF or CEST-MRF method.

The proposed method is more effective at correcting the intensity nonuniformity of phased-array surface-coil images than the conventional SOS method. In addition, the method was shown to be resilient to noise and was successfully applied for image reconstruction in parallel imaging.