성균관대학교 · 의학
Jae-Hoon Ko 교수의 연구실은 감염병의 면역학적 반응과 진단 기술 개발을 중심으로 연구를 진행하고 있습니다. 특히 코로나19와 같은 바이러스 감염에 대한 빠른 항체 진단법 개발, 면역 기억 T세포 반응의 변이체 대비 특이성 분석, 그리고 허혈성 질환 등에서의 바이러스 재활성화 위험 요인 규명에 중점을 두고 있습니다. 최근에는 3D 이미지 재구성 기술과도 연계해 면역 반응의 다차원적 분석 기법을 탐색하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Most asymptomatic and mild COVID-19 patients produced the neutralizing antibody, although the titers were lower than pneumonia patients. ELISA and FIA sensitively detected anti-SARS-CoV-2 antibodies.
Steroid use and RBC transfusion within 1 month of the diagnosis of colitis were independent risk factors for development of CMV colitis in immunocompetent hosts.
With the recent advances in NeRF-based 3D aware GANs quality, projecting an image into the latent space of these 3D-aware GANs has a natural advantage over 2D GAN inversion: not only does it allow multi-view consistent editing of the projected image, but it also enables 3D reconstruction and novel view synthesis when given only a single image. However, the explicit viewpoint control acts as a main hindrance in the 3D GAN inversion process, as both camera pose and latent code have to be optimized
A large HAdV outbreak is currently ongoing in the Korean military, with a trend away from seasonality, and HAdV-55 is likely the predominant strain. Persistent efforts to control the outbreak, HAdV type-specific surveillance, and vaccine development are required.
Here, we examine peripheral blood memory T cell responses against the SARS-CoV-2 BA.4/BA.5 variant spike among vaccinated individuals with or without Omicron breakthrough infections. We provide evidence supporting a lack of original antigenic sin in CD8<sup>+</sup> T cell responses targeting the spike. We show that BNT162b2-induced memory T cells respond to the BA.4/BA.5 spike. Among individuals with BA.1/BA.2 breakthrough infections, IFN-γ-producing CD8<sup>+</sup> T cell responses against the
