Jae‐Joong Lee
성균관대학교 뇌인지과학과 · 신경과학
이 교수의 연구실은 뇌의 통증과 쾌락을 뇌 기능망과 신경가시화 기법을 통해 탐구하는 데 초점을 맞추고 있습니다. 특히 지속적인 통증과 쾌락의 뇌 기반 공통 표현 체계, 동적 기능적 연결성, 개인 맞춤형 뇌 디코딩 기술 개발을 핵심 연구 방향으로 삼고 있습니다. fMRI 및 전기자기적 생체 신호 분석을 기반으로 통증의 신경생물학적 지표를 규명하고 있으며, 임상적 적용 가능성을 고려한 신뢰도 높은 신경생물지표 개발에 주력하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Pain is constructed through complex interactions among multiple brain systems, but it remains unclear how functional brain networks are reconfigured over time while experiencing pain. Here, we investigated the time-varying changes in the functional brain networks during 20 min capsaicin-induced sustained orofacial pain. In the early stage, the orofacial areas of the primary somatomotor cortex were separated from other areas of the somatosensory cortex and integrated with subcortical and frontopa
Pleasure and pain are two fundamental, intertwined aspects of human emotions. Pleasurable sensations can reduce subjective feelings of pain and vice versa, and we often perceive the termination of pain as pleasant and the absence of pleasure as unpleasant. This implies the existence of brain systems that integrate them into modality-general representations of affective experiences. Here, we examined representations of affective valence and intensity in an functional MRI (fMRI) study (<i>n</i> =
In order to present that the electromagnetic compatibility standards following the frequency goes up which is based automotive electronics, in this paper, a hybrid/electric vehicle battery which reflects the frequency of the equivalent circuit model is introduced. By using this circuit modeling, the impedance characteristics can be analysed and an analyze of battery one cell is finished. Using this model, each different from the discharging situation, the discharge characteristic curve could be
This dataset includes behavioral data and analysis-derived outputs from fMRI data associated with the following study:Jae-Joong Lee, Seongwoo Jo, Sungkun Cho, Choong-Wan Woo, Personalized Brain Decoding of Spontaneous Pain in Individuals With Chronic Pain, 2026, <i>Nature Neuroscience</i>For more information about preprocessing and analysis code accompanying the data, please visit the following repository: https://github.com/cocoanlab/DEIPP
ABSTRACT Pleasure and pain are two opposites that compete and influence each other, implying the existence of brain systems that integrate them to generate modality-general affective experiences. Here, we examined the brain’s general affective codes (i.e., affective valence and intensity) across sustained pleasure and pain through an fMRI experiment ( n = 58). We found that the distinct sub-populations of voxels within the ventromedial and lateral prefrontal cortices, the orbitofrontal cortex, t
A bstract Pain is constructed through complex interactions among multiple brain systems, but it remains unclear how functional brain network representations are dynamically reconfigured over time while experiencing pain. Here, we investigated the dynamic changes in the functional brain networks during 20-min capsaicin-induced sustained orofacial pain. In the early stage, the orofacial areas of the primary somatomotor cortex were separated from the other primary somatomotor cortices and integrate
This dataset includes behavioral data and analysis-derived outputs from fMRI data associated with the following study:Jae-Joong Lee, Seongwoo Jo, Sungkun Cho, Choong-Wan Woo, Personalized Brain Decoding of Spontaneous Pain in Individuals With Chronic Pain, 2026, <i>Nature Neuroscience</i>For more information about preprocessing and analysis code accompanying the data, please visit the following repository: https://github.com/cocoanlab/DEIPP
This dataset includes behavioral data and analysis-derived outputs from fMRI data associated with the following study:Jae-Joong Lee, Seongwoo Jo, Sungkun Cho, Choong-Wan Woo, Personalized Brain Decoding of Spontaneous Pain in Individuals With Chronic Pain, 2026, <i>Nature Neuroscience</i>For more information about preprocessing and analysis code accompanying the data, please visit the following repository: https://github.com/cocoanlab/DEIPP
Detecting depression from conversational text using large language models (LLMs) has garnered significant interest. However, the limited interpretability of existing methods presents a major challenge for clinical application. To address this, we propose a novel framework for automatic depression assessment, which employs LLM prompting to extract interpretable factors linked to depression from text and uses linear regression to predict severity scores. We evaluated our approach using a benchmark
This dataset contains de-identified functional magnetic resonance imaging (fMRI) and dynamic functional connectivity data, and the self-reported pain ratings.<br>For more information, please visit out GitHub repository (https://github.com/cocoanlab/tops)!<br>Paper title: "A neuroimaging biomarker for sustained experimental and clinical pain"
This dataset includes behavioral data and analysis-derived outputs from fMRI data associated with the following study:Jae-Joong Lee, Seongwoo Jo, Sungkun Cho, Choong-Wan Woo, Personalized Brain Decoding of Spontaneous Pain in Individuals With Chronic Pain, 2026, <i>Nature Neuroscience</i>For more information about preprocessing and analysis code accompanying the data, please visit the following repository: https://github.com/cocoanlab/DEIPP