Jaeryung Oh
고려대학교 의과대학 안과학교실 · 의학
오재영 교수의 연구실은 망막 및 망막하 조직의 구조적 변화와 혈관 기능 이상이 연령 관련 황반변성(AMD) 및 중심세론막병증(CSC) 등의 망막질환에서 어떻게 작용하는지에 중점을 두고 있습니다. 특히, 고해상도 산란광학간섭단층촬영(SD-OCT)과 혈관형광단층촬영(angiography)을 활용해 망막외층의 손상, 망막혈관 및 망막하혈관망의 변화를 정량적으로 분석하고 있습니다. 연구는 망막 구조와 혈류 변화 간의 상관관계를 규명함으로써, 조기 진단 및 질환 진행 예측에 기여하고자 합니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
BCVA after MHS correlates with objectively ascertainable SD-OCT measurements of IS/OS defects and other features. The postoperative area of the IS/OS defect, when directly measured, correlates more strongly with BCVA than do linear-based measurements, perhaps because of the irregular shape of the IS/OS defect after surgery.
In addition to vascular insufficiency in the choroid or choriocapillaris, retinal vascular alteration was apparent in eyes with early AMD. It may suggest that retinal vessels were involved in the pathogenesis of AMD even while changes in nonvascular components of the retina were not yet apparent.
Vascular density of choriocapillaris varies with retinal vascular density rather than the structure of choroid using optical coherence tomography angiography. In contrast, retinal vascular density changes as the retinal structure. Our results provide more information about the relationship between retina and choroid.
Subfoveal CT was thinner in early AMD patients with RPD than in those without RPD. Lower baseline mean OPP and a history of systemic hypertension could be risk factors associated with the progression of choroidal thinning in early AMD patients with RPD.
Lesions exhibiting retinal opacity characteristic of commotio retinae corresponded to hyperreflective outer segment lesions without the increase in retinal thickness on spectral-domain optical coherence tomography.
Biometric characteristics such as AL and ACD were different between eyes with CSC and fellow eyes. Variations in biometry, which correlated with CT differences, might be related to differences in refractive errors between eyes.
Neither author has a financial or proprietary interest in any material or method mentioned.
Characteristics of cystoid spaces of eyes with MacTel 2 were different from those in eyes with MacTel 1, retinal vein occlusion, and diabetic macular edema. The irregular boundaries and low reflectivity of the cystoid spaces in MacTel 2 may represent the degenerative origin of the disease.
The measurement of choroidal thickness on peripapillary circle scan images for RNFL analysis using the 3D-OCT viewing program was highly reliable and efficient.
Toxoplasmic retinal vasculitis should be considered as a cause of frosted branch angiitis.
