Ji-Yeon Yang
연세대학교 Department of Environmental Engineering · 환경과학
Ji-Yeon Yang 교수의 연구실은 환경독소와 외부 노출 요인에 기인한 건강 위험을 평가하고, 이를 바탕으로 예방 및 정책 수립에 기여하는 연구를 중심으로 전개하고 있습니다. 주로 환경 오염물질(미세먼지, 흡연 연기, 인공잔디 등에서 유출되는 유해화학물질)이 인체에 미치는 영향과 그 생체 반응을 분석하며, 특히 흡연 연기(제2의, 제3의 연기)와 기후 변화 및 도시 환경 요인과 관련된 질병 발생 위험을 생물학적 지표와 연계해 연구하고 있습니다. 또한, 자연물 유래 화합물이 기생충 및 병원성 미생물에 미치는 영향을 탐색함으로써 환경 기반 예방 전략을 모색하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Soy products are mainly composed of proteins, phytochemicals such as isoflavones, soy lipids, and carbohydrates. It is unclear whether an individual component alone or a combined effect of multiple bioactive compounds contributes to the beneficial properties of soy. We investigated the effect of dietary genistein (the principal soy isoflavone) alone and combined with L-carnitine to evaluate possible synergistic effects on the intentionally induced prediabetic state characterized by insulin resis
Patients with ovarian cancer are at high risk of tumor recurrence. Prediction of therapy outcome may provide therapeutic avenues to improve patient outcomes. Using reverse-phase protein arrays, we generated ovarian carcinoma protein expression profiles on 412 cases from TCGA and constructed a PRotein-driven index of OVARian cancer (PROVAR). PROVAR significantly discriminated an independent cohort of 226 high-grade serous ovarian carcinomas into groups of high risk and low risk of tumor recurrenc
Our work provides valuable insight into the drug induced cell fusion event and outcome, and suggests YB-1, GST, ABCB5 and ERK3 could be potential targets for the anti-cancer drug development against drug resistant breast cancer cells. Especially, the ERK-3 serine/threonine kinase is specifically up-regulated in the resistant cells and known to be susceptible to synthetic antagonists.
With globalization and digitalization, participating in Global Value Chain (GVC) and developing digital economy have had a profound impact, which transforms China’s economy into a green and innovative one. This paper studies the intrinsic influential mechanism of GVC embeddedness and digital economy on green innovation and proposes some research hypotheses. Based on panel data of 30 Chinese provinces from 2002 to 2016, we constructed some core indicators such as GVC embeddedness, digital economy
Exposure to environmental tobacco smoke (ETS) is the reason for approximately 1% of global mortality. ETS exposure can happen either as inhalation of direct cigarette smoke (second-hand smoke) or its associated residue particles (third-hand smoke), especially when living with a smoker in the same family. This study investigated the association between the urinary cotinine levels, as biomarkers of exposure to tobacco smoke, of smokers and those exposed to second-hand and third-hand smoke while li
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by SFTS virus with 12-30% fatality rate. Despite severity of the disease, any medication or treatment for SFTS has not developed yet. One approach to prevent SFTS spreading is to control the arthropod vector carrying SFTS virus. We report that 2-methylbenzaldehyde analogues from M. officinalis have a dual function as acaricide against Dermatophagoides spp. and Haemaphysalis longicornis and indicator (colo
