Jinyoung Kim
연세대학교 공과대학 · 공학
김진영 교수의 연구실은 마이크로유체 및 나노소재 기반의 바이오디스플레이 및 약물 개발 플랫폼을 핵심으로 연구를 전개하고 있습니다. 특히, 금속 나노입자 기반의 바이러스 진단 및 치료, 다세포 구조를 모사한 장기-온-어-칩 시스템, 그리고 고성능 마이크로유체 디바이스를 활용한 약물 스크리닝 기술 개발에 주력하고 있습니다. 이러한 연구들은 약물 개발의 정밀도와 효율성을 높이고, 동물 실험 대체 및 개인 맞춤형 치료 전략 개발에 기여하고자 합니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
We believe that the technique described herein can be further developed for PoGNP-utilized antiviral protection as well as metal nanoparticle-based therapy to treat viral infection. Additionally, facile detection of IAV can be achieved by developing PoGNP as a multiplatform for detection of the virus.
In this article, we present a microfluidic platform, compatible with conventional 96-well formats, that enables facile and parallelized culturing and testing of spherical microtissues in a standard incubator. The platform can accommodate multiple microtissues (up to 66) of different cell types, formed externally by using the hanging-drop method, and enables microtissue interconnection through microfluidic channels for continuous media perfusion or dosage of substances. The platform contains 11 s
We demonstrate the integration of a droplet-based microfluidic device with high performance liquid chromatography (HPLC) in a monolithic format. Sequential operations of separation, compartmentalisation and concentration counter were conducted on a monolithic chip. This describes the use of droplet-based microfluidics for the preservation of chromatographic separations, and its potential application as a high frequency fraction collector.
The vast majority of droplet-based microfluidic devices are made from polydimethylsiloxane (PDMS). Unfortunately PDMS is not suitable for high frequency droplet generation at high operating pressure due to its low shear modulus. In this paper, we report the fabrication and testing of microfluidic devices using thermoset polyester (TPE). The optical characteristics of the fabricated devices were assessed and substrate resistance to pressure also investigated. TPE devices bonded using an O(2) plas
The<i>in vitro</i>simulation of organs resolves the accuracy, ethical, and cost challenges accompanying<i>in vivo</i>experiments. Organoids and organs-on-chips have been developed to model the<i>in vitro</i>, real-time biological and physiological features of organs. Numerous studies have deployed these systems to assess the<i>in vitro</i>, real-time responses of an organ to external stimuli. Particularly, organs-on-chips can be most efficiently employed in pharmaceutical drug development to pre
Group theoretical methods were applied to elucidate the structural transition path and the polarization process in YMnO3. The atomic displacements derived from in situ high-temperature synchrotron x-ray powder diffraction data were decomposed into three symmetry-adapted modes (Γ2−, K1, and K3). The temperature dependence of the mode amplitudes confirmed the existence of two step-transitions. First, a coupled K3 and Γ2− mode lowered the symmetry from P63/mmc to P63cm at the phase-transition tempe
Recently, deep learning models proliferate in the prediction of power demand for efficient planning of power consumption. However, the “black-box” characteristics of deep learning hinders from establishing a specific plan because it cannot explain the cause of the prediction. Recently, there are several attempts to explain the result of deep learning through the analysis of the input attributes that influence the prediction, but they lack of appropriate explanation because of ignoring the time-s