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High affinity and selective detection for PPi is exhibited by a new fluorescent sensor based on a naphthalene–dpa system (see picture). The binuclear zinc complex is remarkably selective toward PPi over other anions. For example, PPi can be detected at micromolar concentrations in the presence of a large excess of ATP. PPi=pyrophosphate, ATP=adenosine triphosphate, dpa=bis(2-pyridylmethyl)amine.

Synthesis and complexation behavior of ditopic neutral receptors composed of both a Lewis-acidic binding site (zinc porphyrin moiety) and a Lewis-basic binding site (crown ether moiety) are reported; the receptors bound only NaCN in a ditopic fashion with a color change, and in contrast other sodium salts bound to the receptors in a monotopic fashion without a color change.

The need to decipher various biological events has led to the elucidation of the molecular mechanisms underlying a number of disease processes. Consequently, the detection and simultaneous monitoring of chemical interactions between biological targets has become indispensable in medical diagnosis, targeted therapeutics, and molecular biology. Multiplexed applications employing nanomaterials, which represent the integration of nanotechnology and biology, have changed the bioanalytical outlook and

We have successfully developed a fluoride ion probe for fluorescence cell bioimaging-desirable properties include retention of the fluorophore inside cells, non-cytotoxicity to mammalian cells, appreciable solubility in water, and stoichiometric reaction with analytes.

A new anion sensor 1 with an azophenol and p-nitrophenyl moieties as chromophores allows for easy colorimetric differentiation of F−, H2PO4− and AcO− with similar basicity.

A new carbazole derivative with two carbazole moieties on the C3 and C6 positions of carbazole and triphenylsilane directly linked to the N of carbazole is successfully used as a highly efficient blue phosphorescent host in an organic light-emitting diode (PhOLED). The blue PhOLED, with this new host, gives an extremely high external quantum efficiency.

A new fluorescent sensor based on a pyrene/Zn(II)-dpa (dpa = bis(2-pyridylmethyl)amine) conjugate displays excimer emission selective for pyrophosphate over other anions.

Replication and mutation are necessary elements of evolution, and some properties of self-replicating molecules (replicators) can be explored with synthetic structures. Selection and evolution at the molecular level require systems capable of competition and inheritable change. These phenomena have now been observed with synthetic molecules. Two such molecules were prepared having sufficient structural similarity that they catalyzed each other's formation as well as their own. One of the replica

Electrodes made by depositing ruthenium oxide on conducting poly(3,4-ethylenedioxythiophene) (PEDT) were studied for their electrochemical and impedance properties. In acidic electrolytes the composite electrodes exhibited large capacitance due to contributions from the double-layer capacitance and the faradaic capacitance. Optimization of the thickness of the conducting polymer film and the amount of ruthenium deposition was found necessary to realize large specific capacitance. The specific ca

The self-assembly of molecules in a gel by strong pi-pi stacking interactions between the thienylvinylene anthracene backbones and van der Waals interactions between the long alkyl chains has generated nanofibers; from the organogels, organic single-nanofiber transistors were successfully embodied.