오종민 교수

Previously synthesized novel chalcone oxime ethers (COEs) were evaluated for inhibitory activities against monoamine oxidases (MAOs) and acetylcholinesterase (AChE). Twenty-two of the 24 COEs synthesized, except <b>COE-17</b> and <b>COE-24</b>, had potent and/or significant selective inhibitory effects on MAO-B. <b>COE-6</b> potently inhibited MAO-B with an IC₅₀ value of 0.018 µM, which was 105, 2.3, and 1.1 times more potent than clorgyline, lazabemide, and pargyline (reference drugs

Abstract Luminescent perovskite structure has been used in a polymer‐encapsulated form for display applications. However, insulating polymers as a host matrix are intrinsically vulnerable to thermal stresses which cause softening distortion or deterioration in thermoplastic polymers. Here, nanostructured CsPbBr 3 /Al 2 O 3 composite film is developed by aerosol deposition method. At first, CsPbBr 3 /Al 2 O 3 composite powders with bright and saturated green emission are synthesized. Then, the ce

One hundred and seventy seven acetone extracts of lichen and 258 ethyl acetate extracts of cultured lichen-forming fungi (LFF) were screened for antimicrobial activity against <i>Staphylococcus aureus</i> and <i>Enterococcus faecium</i> using a disk diffusion method. Divaricatic acid was isolated from <i>Evernia mesomorpha</i> and identified by LC-MS, ¹H-, ¹³C- and DEPT-NMR. Purified divaricatic acid was effective against Gram + bacteria, such as <i>Bacillus subtilis</i>, <i>Staphyloc

Abstract Although the unique nanostructure of bacterial cellulose (BC) imparts superior mechanochemical properties and thus allows for diverse applications, the high production cost of BC necessitates the development of more cost‐effective solutions, for example, those using lignocellulosic biomass as a substrate and relying on its pretreatment and saccharification to generate fermentable sugars. However, the various species (e.g., aliphatic acids, furans, and phenolics) produced during pretreat

Among 276 herbal extracts, a methanol extract of Castanopsis cuspidata var. sieboldii stems was selected as an experimental source for novel acetylcholinesterase (AChE) inhibitors. Five compounds were isolated from the extract by activity-guided screening, and their inhibitory activities against butyrylcholinesterase (BChE), monoamine oxidases (MAOs), and β-site amyloid precursor protein cleaving enzyme 1 (BACE-1) were also evaluated. Of these compounds, 4'-O-(α-L-rhamnopyranosyl)-3,3',4-tri-O-m

Respiration monitoring and human sweat sensing have promising application prospects in personal healthcare data collection, disease diagnostics, and the effective prevention of human-to-human transmission of fatal viruses. Here, we have introduced a unique respiration monitoring and touchless sensing system based on a CsPb₂Br₅/BaTiO₃ humidity-sensing layer operated by water-induced interfacial polarization and prepared using a facile aerosol deposition process. B

This study presents concentrations of iron, zinc, copper, lead and cadmium in the feathers of 3 shorebird species (n = 29) from Okgu Mudflat, Korea in the East Asian-Australian Migration Flyways. Lead concentrations (ANOVA, p < 0.001) in Red-necked Stints (geomean = 9.61 μg g(-1) dry weight) were higher than in Terek Sandpipers (geomean = 5.56 μg g(-1) dry weight) which in turn were higher than in Great Knots (geomean = 2.78 μg g(-1) wet weight). Cadmium concentrations (ANOVA, p < 0.001) were hi