연세대학교 · 치의학
Jung-Seok Lee 교수의 연구실은 치주조직 재생과 뼈 재생을 위한 생체모방재료 및 성장인자 기반의 치료 전략 개발에 중점을 두고 있습니다. 특히 rhGDF-5, rhBMP-2, DPBM, DBBM 등의 생체재료를 활용한 릉 재건 및 틈새 보존 기법에 대한 임상적 유효성과 장기적 안정성을 평가하고 있습니다. 디지털 측정 기술의 정확성과 신뢰성에 대한 연구를 통해 정밀한 임상 평가 방법의 표준화를 추구하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
rhGDF-5/beta-TCP has a greater potential to support the regeneration of the periodontal attachment. Long-term studies are necessary to confirm the uneventful maturation of the regenerated tissues.
DBBM and DPBM can comparably augment damaged extraction sockets with minimal postoperative reduction of the grafted volume. However, the large variations in the results should be further evaluated for application in routine dental clinics.
Buccal-bone-deficiency may lead to significant volume reduction after tooth extraction along the entire length of the socket, and socket grafting accompanied by rhBMP-2 or covered with a membrane can be candidate therapies for preservation of the buccolingual dimension and successful ridge regeneration.
The results suggested that DPBM might produce comparable bone formation and volumetric stability with DBBM in maxillary sinus grafting, however, further clinical study with longer-term periods and larger sample sizes should be needed for confirming this suggestion.
In conclusion, the findings of this study suggest that NIs could be used safely for narrow alveolar ridges or narrow mesiodistal spaces on the basis of their high survival rate.
This study aimed to compare the accuracy and reliability of digital versus conventional clinical measurements of the width of keratinized tissue. To this end, the keratinized tissue width was measured at 110 tooth sites in 5 pig jaws. The measurements were made at each site using three-dimensional (3D) scanned images and a periodontal probe. The actual keratinized tissue width was subsequently measured on histologic slides prepared from the same sites, and differences between the histologic slid
Comparable histologic bone formation was found in both socket grafted groups with DBBM or DPBM covered by collagen membranes in periodontally damaged extraction sockets. However, a wide variation in new bone formation was found after 4 months of postsurgical healing and a tendency of higher new bone formation was shown at damaged sockets that had an intact unilateral residual wall regardless of buccal or lingual side.
In the limitation of this study, customized n-HA block could provide a space for periodontal tissue engineering, with minimal inflammation.
Straumann tissue-level dental implants showed low failure rates and can be considered a useful long-term treatment option. The length, placement site, and insertion torque might affect implant survival.
Using a three-dimensionally printed surgical template with a nonmetal sleeve in the partial edentulous ridge resulted in larger deviations in implants placed in the mandible or distal free-end third or fourth nearest site.