Justin Sangwook Ko
성균관대학교 의예과 · 의학
Justin Sangwook Ko 교수의 연구실은 장기 기증자 및 수혜자의 안전성을 최우선으로 삼는 간장기증 및 간이식 분야의 임상적 연구를 중심으로 전개됩니다. 특히 기증자의 통증 관리 전략, 지방간 여부가 허혈/재순환 손상에 미치는 영향, 기증자 성별이 암 복귀 및 이식 합병증에 미치는 영향 등 기증자 특성과 이식 성과의 상관관계를 깊이 있게 분석하고 있습니다. 또한 수혈의 영향과 혈소판 수치가 간세포암 복귀에 미치는 영향 등 생물학적 기전과 임상적 결과를 연결지어 연구하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
The healthy condition of living donors makes their tolerance to pain particularly low, and clinicians are often challenged to come up with an analgesic technique that is effective yet ensures donor safety. This study compared, in donor right hepatectomy, the efficacy and safety of preoperative intrathecal morphine (ITM) combined with intravenous patient-controlled analgesia (IV-PCA) with IV-PCA alone. Forty adult patients were randomly allocated into 2 groups: ITM+IV-PCA group (n = 20) and IV-PC
Platelets interact with tumor cells and promote metastasis. The importance of platelets in posttransplant hepatocellular carcinoma (HCC) recurrence is unclear. Thus, we aimed to evaluate the association between preoperative platelet count (PLT) and HCC recurrence after living donor liver transplantation. Of 359 recipients of livers from living donors for HCC, 209 of 240 patients who had preoperative PLT ≤75 × 10<sup>9</sup> /L were matched with 97 of 119 patients who had preoperative PLT >75 × 1
A safe use of intermittent hepatic inflow occlusion (IHIO) has been reported for living donor hepatectomy. However, it remains unclear whether the maneuver is safe in steatotic donors. In addition, the respective importance of macrosteatosis (MaS) and microsteatosis (MiS) is an important issue. Thus, we compared MiS and MaS with respect to the tolerance of hepatic ischemia/reperfusion (IR) injury induced by IHIO. One hundred forty-four donors who underwent a right hepatectomy were grouped accord
Our findings suggest a potential negative impact of fresh RBC transfusion on the survival of patients undergoing liver transplantation.
Donor sex appears to be an important graft factor modulating HCC recurrence after living donor liver transplantation.
Donor sex appears to be an independent factor modulating graft failure risk in male liver transplant recipients.
