Justin Y. Jeon
연세대학교 의과대학 · 의학
Justin Y. Jeon 교수의 연구실은 비만, 대사증후군 및 당뇨병과 관련된 대사 및 호르몬 조절 메커니즘을 중심으로 연구를 진행하고 있습니다. 특히 체성지방 조절에 관여하는 호르몬( adiponectin, leptin, chemerin, MCH 등)과 신체 구성, 기초 대사율, 인슐린 감수성 간의 상관관계를 체계적으로 분석하고 있으며, 운동 및 생활습관 개선이 대사질환 예방 및 관리에 미치는 영향을 기초 및 임상 연구로 검증하고 있습니다. 또한 대장암 생존자 대상의 운동 프로그램 적용을 통해 치료 후 삶의 질 향상 방안을 모색하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Obese Korean male adolescents showed reduced adiponectin levels and increased inflammatory cytokines. Six weeks of jump rope exercise improved triglyceride and insulin sensitivity and increased adiponectin levels.
A 12-week intensive lifestyle intervention significantly decreased serum chemerin level compared to usual care. Decrease in serum chemerin level was associated with improved insulin sensitivity, and this may be involved in the beneficial effects of lifestyle intervention in overweight and obese type 2 diabetic patients.
Compared with able-bodied (AB), people with spinal cord injury (SCI) have a 3- to 5-fold higher risk of developing type 2 diabetes mellitus, which may be associated with increased fat mass. Evidence suggests that leptin regulates body adiposity through the sympathetic nervous system, which is impaired in people with high lesion SCI. The purpose of this study was to determine the relationship among leptin levels, body composition, and resting metabolic rate (RMR) in people with high lesion SCI an
Ablation of the hypothalamic peptide, melanin-concentrating hormone (MCH), leads to a lean phenotype and resistance to diet-induced obesity. Observation of MCH(-/-) mice at older ages suggested that these effects persist in mice >1 year old. Leanness secondary to caloric restriction is known to be associated with improved glucose tolerance as well as an overall increase in life span. Because the MCH(-/-) model represents leanness secondary to increased energy expenditure rather than caloric rest
Despite improvement in prognosis of colorectal cancer, colorectal cancer survivors often suffer from adverse effects of cancer treatment, including reduced health-related fitness level. Therefore, this study aimed to examine the feasibility and efficacy of the 6-week home-based exercise program on the level of physical activity and physical fitness in stage II to III colorectal cancer survivors. Seventy-two stage II to III colorectal cancer survivors were randomly assigned to either a home-based
This study suggests that DM negatively impacts survival outcomes of patients with colon cancer but not rectal cancer.
