Hokkaido University · 신경과학
켄지 오가와 교수의 연구실은 신체 운동 제어와 인지기능의 신경기반 메커니즘을 밝히는 데 초점을 맞추고 있습니다. 특히 시각적 자극에 기반한 운동 조정, 내재된 운동 모니터링, 자극-행동 간의 상호작용에서 발생하는 인지적 간섭과 적응 메커니즘을 fMRI를 활용해 분석합니다. 복잡한 운동 제어 과정에서 뇌의 특정 영역이 어떻게 공간 기준좌표를 처리하고, 문장 이해나 다국어 문장 해석과 같은 인지적 작업을 수행하는지에 대한 신경기반 모델을 구축하고자 합니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Internal monitoring or state estimation of movements is essential for human motor control to compensate for inherent delays and noise in sensorimotor loops. Two types of internal estimation of movements exist: self-generated movements, and externally generated movements. We used functional magnetic resonance imaging to investigate differences in brain activity for internal monitoring of self- versus externally generated movements during visual occlusion. Participants tracked a sinusoidally movin
Behavioral studies have shown that humans can adapt to conflicting sensorimotor mappings that cause interference after intensive training. While previous research works indicate the involvement of distinct brain regions for different types of motor learning (e.g., kinematics vs dynamics), the neural mechanisms underlying joint adaptation to conflicting mappings within the same type of perturbation (e.g., different angles of visuomotor rotation) remain unclear. To reveal the neural substrates tha
Abstract The neural mechanisms underlying visuomotor transformation are examined based on deficits in tracing and copying, as well as functional neuroimaging studies. The developmental process of copying and tracing, as well as lesion studies with adults showing disability in drawing, are reviewed, then two experiments are introduced. In Experiment 1, a behavioral analysis of copying and tracing by individuals with Williams Syndrome (WS) was presented. In Experiment 2, the brain activity involve
This study used event-related functional magnetic resonance imaging to investigate the neural basis underlying the sequential involvement of syntactic processing in the course of sentence comprehension. In experiments, a noun, case particle, and verb were presented one by one, constituting simple sentences in Japanese. Participants judged whether the sentence was syntactically correct (syntactic judgment) or whether the particle and verb had the same vowel (phonological judgment). During particl
While common semantic representations for individual words across languages have been identified, a common meaning system at sentence-level has not been determined. In this study, fMRI was used to investigate whether an across-language sentence comprehension system exists. Chinese-Japanese bilingual participants (<i>n</i> = 32) were asked to determine whether two consecutive stimuli were related (coherent) or not (incoherent) to the same event. Stimuli were displayed with three different modalit
Visually guided reaching involves the transformation of a spatial position of a target into a body-centered reference frame. Although involvement of the posterior parietal cortex (PPC) has been proposed in this visuomotor transformation, it is unclear whether human PPC uses visual or body-centered coordinates in visually guided movements. We used a delayed visually guided reaching task, together with an fMRI multivoxel pattern analysis, to reveal the reference frame used in the human PPC. In exp