Keum Taek Hwang
서울대학교 생활과학대학 · 농업·생명과학
황근탁 교수의 연구실은 식물 유래 천연물, 특히 귀리, 밀, 블랙라스베리 등에서 유래한 생활화학적 성분의 분리, 정제 및 생리활성 평가를 중심으로 연구를 진행하고 있습니다. 주요 연구 분야는 항산화 및 항염증 작용을 보이는 탄닌류(특히 에라기타닌 및 유로리틴)의 생체이용가능성과 항암 메커니즘 규명이며, 천연 왁스 및 폴리코사놀 등 기능성 지방질 성분의 분석 및 산업적 응용 가능성을 탐색하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Abstract Grain sorghum wax has been judged to be a potential source of natural wax with properties similar to carnauba wax. Approximately 0.16–0.3% (w/w) wax can be extracted from grain sorghum depending on the efficiency of the organic solvents. Although the melting points of carnauba wax and sorghum wax are similar, i.e., 78–86 and 77–85°C, respectively, they differ in acid values, i.e., 2–10 and 10–16, respectively, and saponification numbers, i.e., 77–95 and 16–49, respectively. Improved kno
Black raspberry seed extract and its tannin fraction were characterized and their antioxidant and anti-inflammatory activities were compared to grape seed extract and its tannin fraction. Tannin fraction of black raspberry seed extract was mostly composed of ellagitannins including pedunculagin, sanguiin H6 and H10 isomers and galloyl-bis-HHDP glucose isomer, while that of grape seed extract was composed of proanthocyanidins including proanthocyanidin dimers, trimers, tetramers, pentamers, their
Black raspberry (BRB) seeds are a major waste product after fruit processing. The seeds are abundant in ellagitannins (ET), a class of hydrolysable tannins, which are hydrolyzed to ellagic acid (EA) and further metabolized to urolithin A (UA) and urolithin B (UB), known to be bioavailable in the colon and the prostate. In this study, the anti-cancer activities of these compounds were evaluated on HT-29 colon cancer cells. ET, EA, UA and UB inhibited the proliferation of the cancer cells. EA caus
ABSTRACT Several antioxidants as well as vacuum packaging and changes in frozen storage temperatures (‐7°C and ‐20°C) were tested for their effect on the peroxide values and free fatty acids (FFA) of frozen minces from Gulf menhaden, Brevoortia patronus and Atlantic men‐haden, Brevoortia tyrannus. Vacuum packaging was the most effective in retarding oxidative rancidity. Storage at ‐20°C also reduced the oxidation versus ‐7°C. Ascorbic acid and crythorbic acid had the best antioxidant activity of
Correction for 'Chemopreventive activity of ellagitannins and their derivatives from black raspberry seeds on HT-29 colon cancer cells' by Hyunnho Cho et al., Food Funct., 2015, 6, 1675-1683.
ABSTRACT Grain sorghum can be a major source of policosanols, long‐chained alcohols, that have beneficial physiological activities. Sorghum dried distillers grains (DDG), a by‐product of ethanol production from grain sorghum, contain a large amount of policosanols. Content and composition of policosanols in long‐chained lipids extracted from grain sorghum kernels and DDG were determined. Long‐chained lipids were extracted using hot hexane or hot ethanol. The major components of the long‐chained
A method to detect 7‐ketocholesterol, cholesterol‐5β,6β‐epoxide, cholesterol‐5α,6α‐epoxide, 4‐cholesten‐3‐one, 4,6‐cholestadien‐3‐one and 4‐cholestene‐3,6‐dione in unirradiated and irradiated beef, pork and veal was developed by use of chloroform‐methanol‐water extraction, solid‐phase extraction, column separation, thin‐layer chromatography and gas chromatography. This method recovered 78–88% of the cholesterol oxidation products and detected the cholesterol oxidation products at 10 ppb or highe
ABSTRACT The lipid hydrolysis products in minced mackerel stored under vacuum at 2–3°C for 15 days were free fatty acids (FFA) and 1,2‐diglycerides (DG); no 1,3‐DG br monoglycerides were obsrved, Lysophosphati‐dylcholine fLPC and lvsoohosohatidvlethanolamine (LPE) increased and then ddcreased with time: Lysiphosphatidylserie was not observed. More FFA, 1,2‐DG, LPC, and LPE were detected in dark muscle than in light muscle. The initial fatty acid composition, by GC, showed no significant differen
<i>Lactobacillus plantarum</i> PMO 08 was evaluated as a starter culture for plant-based probiotic beverages. Its viability under various culture conditions and acidification ability in standardized tomato medium, fermentation parameters, and beverage properties were assessed. <i>Lactobacillus plantarum</i> PMO 08 could grow under various culture conditions; there was a high correlation between the incubation time to reach the optimal conditions and the inoculation concentration of lactic acid b
Choline is converted to trimethylamine by gut microbiota and further oxidized to trimethylamine-<i>N</i>-oxide (TMAO) by hepatic flavin monooxygenases. Positive correlation between TMAO and chronic diseases has been reported. Polyphenols in black raspberry (BR), especially anthocyanins, possess various biological activities. The objective of this study was to determine the effects of BR extract on the level of choline-derived metabolites, serum lipid profile, and inflammation markers in rats fed