Kyo Seon Hwang
경희대학교 의과대학·의학전문대학원 · 공학
Kyo Seon Hwang 교수의 연구실은 나노기계적 미세캔틸레버를 활용한 고감도 라벨프리 생체 감지 기술을 핵심으로 연구를 진행하고 있습니다. 특히, 표면 응력 변화를 정밀하게 측정함으로써 프로스테이트특이항원과 같은 생체 분자 간의 상호작용을 실시간으로 감지하는 기술 개발에 주력하고 있으며, MEMS 공정 기반의 고성능 센서 소자를 설계·제작합니다. 이는 진단기기의 소형화, 휴대성 및 빠른 분석을 실현하는 데 기여합니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
We report on a novel technique of resonant frequency shift measurement based on a nanomechanical cantilever with a PZT actuating layer for label-free detection of a prostate-specific antigen (PSA) in a liquid environment. The nanomechanical PZT thin film cantilever is composed of SiO(2)/Ta/Pt/PZT/Pt/SiO(2) on a SiN(x) supporting layer for simultaneous self-exciting and sensing; it was fabricated using a standard MEMS (micro electromechanical system) process. The specific binding characteristics
Recent research trends in biosensing have been geared toward developing bioanalytical devices that are label free, small in size, and portable and that can operate in a rapid manner. The performance of these devices has been dramatically improved through the advent of new materials and micro-/nanofabrication technologies. This is especially true for micro-/nanosized cantilever sensors, which undergo a change in mechanical properties upon the specific binding of biomolecules. In this review, we i
Nanomechanical microcantilevers have played a vital role in detecting biomolecular interactions. The ability of microcantilevers to detect biomolecular interactions is ascribed to the principle that the surface stress, caused by biomolecular interactions, dominates the dynamical response of the microcantilever. Here we have experimentally studied the correlation between biomolecular interactions and the dynamical response of microcantilevers. Moreover, the authors employed a mechanical beam mode
