Nagoya University · 의학
마리코 카와무라 교수의 연구실은 뇌의 림프성 배출 기능과 신경퇴행성질환의 연관성, 특히 수면 중 활성화되는 글리mphatic 시스템의 기능과 기전을 중심으로 신경과학 및 뇌질환의 생물학적 기전을 탐구하고 있습니다. 또한 유방암 치료 분야에서는 국소진행성 유방암의 예후 개선을 위한 신속한 치료 반응 예측 기법과 IORT(일시적 방사선 치료)의 임상적 적용 가능성을 연구하고 있습니다. 특히 MRI 기반의 조기 반응 평가 및 치료 후 합병증 관리에 초점을 맞추고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
The concept of the glymphatic system was proposed more than a decade ago as a mechanism for interstitial fluid flow and waste removal in the central nervous system. The function of the glymphatic system has been shown to be particularly activated during sleep. Dysfunction of the glymphatic system has been implicated in several neurodegenerative diseases. Noninvasive in vivo imaging of the glymphatic system is expected to be useful in elucidating the pathophysiology of these diseases. Currently,
It is reported that <i>Helicobacter pylori</i> (<i>H. pylori</i>) infection may be linked to non-digestive tract diseases, such as arteriosclerosis including dyslipidemia, diabetes, obesity, hypertension, and cardiovascular disease. Therefore, we reviewed recent studies available in PubMed dealing with the mechanisms of arteriosclerosis due to <i>H. pylori</i> infection and the effects of <i>H. pylori</i> eradication. Conventional studies suggested that <i>H. pylori</i> infection may increase th
The first group of female Asian patients tolerated the treatment with IORT in this Phase I/II study and remained recurrence-free for more than 5 years after treatment. However, 24 % of the patients developed hypertrophic scarring, an event that is being further examined in our ongoing multi-center Phase II trial of IORT for early breast cancer.
Neoadjuvant chemotherapy (NAC) is the favored treatment of choice among locally advanced breast cancer patients because it significantly increases the possibility of breast-conserving surgery. However, for non-responders, an early prediction of response to NAC is essential. The purpose of this study was to determine whether an early prediction of response to NAC is possible using MRI. Eleven breast cancer patients (12 lesions) scheduled to receive NAC were recruited for this study. The patients
The use of an immobilizing bra reduced the setup margin for prone position fixation of breast tumors.
Our results suggest that the application of an SCCC regimen such as EP or IP as first-line chemotherapy for patients with locally advanced SCCC may play a key role in OS. These findings need to be validated in future nationwide, prospective clinical studies.
VPS is easy to shape and reproducible. The authors succeeded in demonstrating its safety and accuracy as a proton beam stopper.
