Tohoku University · 의학
마시키 니오 교수의 연구실은 소아 간질환, 특히 담도계기형과 간질환의 조기 진단 및 수술적 치료에 중점을 두고 있습니다. 특히 카사이 포르토항문술(KE)의 적절한 시기 선택과 수술 결과의 연관성을 정밀 분석하며, 소아 간이식 및 복강경 수술 기법의 적용에도 기여하고 있습니다. 장기 생존율 향상과 합병증 최소화를 목표로 한 임상 연구가 중심입니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
There are discrepancies regarding the clinical impact of age at Kasai portoenterostomy (KP) on surgical outcomes. Hence, we re-assessed the clinical significance of age at KP. We analyzed 224 patients with type III (atresia of bile duct at the porta hepatis) biliary atresia at Tohoku University Hospital. We classified patients into two groups: KP at ≤60 days of age (group TE) and >60 days of age (group TL). Group TE was subdivided into three groups (TE1, TE2, and TE3) according to age at time of
Between 1953 and 1995, 300 patients with biliary atresia underwent surgery at Tohoku University Hospital. The 10-year survival of patients who were operated on in or before 1965 was 9%. But the survival rate went up to 61% in patients operated on between 1976 and 1985. Eighty-five patients including 2 who developed liver failure after Kasai operation and underwent liver transplantation have survived more than 10 years. Eleven of them (13%) have recurrent or persistent jaundice. Of the 30 patient