Kyoto University · 의학
메구미 오타 교수의 연구실은 주로 신경영상 및 생체영상 기반의 신경생물학적 기전 규명을 중심으로, 망막 세포층의 구조적 유지와 시력 회복 간의 연관성, 특히 망막의 광수용세포층의 상태가 시력에 미치는 영향을 연구하고 있습니다. 또한, 액정의 정밀 분자 정렬 제어 기술을 활용한 고성능 광학 소자 개발, 특히 q-플레이트 및 회절 웨이브플레이트의 새로운 제조 기법을 개발하여 차세대 광학 기기 응용을 목표로 하고 있습니다. 추가로 만성 요통 환자에서 복부 근육의 두께와 대칭성 변화를 초음파를 이용해 분석함으로써 체내 근육 기능 이상과 통증 간의 연관성을 규명하고자 합니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Integrity of the photoreceptor layer in the fovea is associated with VA in resolved MO, and status of the third HRB before treatment might be predictive of visual outcome.
Liquid crystalline materials with a cycloidal molecular orientation pattern are attractive for fabricating diffractive waveplates, diffracting incident light regardless of its polarization state into left- and/or right-circularly polarized light only in the +1st and/or −1st orders, applicable as next-generation optical devices. However, large-area high-speed processing of such molecular orientation is a challenge, since even state-of-the-art photoalignment methods require a precise spatia
[Purpose] It has been reported that chronic low-back pain (CLBP) patients exhibit asymmetric atrophy of the lumbar multifidus muscle. However, studies focusing on the abdominal muscles have not yet been conducted. The purpose of this study was to determine abdominal muscle thickness and symmetry in CLBP patients and healthy subjects. [Subjects and Methods] Data were obtained from 50 healthy subjects (30.2 ± 6.1 years) and 50 CLBP patients (31.5 ± 8.7 years). The thicknesses of the rectus abdomin
Topological lightwave technologies are expected to be applied in a wide range of emerging optical fields such as q-plates, one of the most attractive devices in this research area, prepared by controlling the high-resolution alignment patterning of liquid crystals. Here, we present a simple and direct fabrication technique of a q-plate that is able to oscillate a vector beam, by employing our newly developed photoalignment concept termed scanning wave photopolymerization (SWaP). SWaP generates p
[Purpose] Therapeutic exercise for chronic low back pain is one of the most important conservative treatments. Recently, lumbar stabilization exercise focused on deep trunk muscles has attracted considerable attention. This study investigated the effectiveness of lumbar stabilization exercises for treating CLBP. [Subjects] The subjects were 18 patients with CLBP. CLBP was defined as pain that persisted for more than 3 months. [Methods] The therapeutic exercises involved the abdominal drawing-in
伝導失語２例の改善過程について，1) 発話に現れる音韻の誤りの経時的変化，2) 聴覚言語性短期記憶 (以下 STM) 検査成績の経時的変化，の２点について観察し，得られた結果をもとに伝導失語の障害メカニズムについて考察を行うことを目的とした。その結果， (1) 呼称，漢字単語の音読，仮名単語の音読，単語の復唱の発話４モダリティーにおいて誤反応の減少に伴い，誤り内容は類推困難な反応や省略・付加の割合が減少し，部分正答，置換，転置が中心となった。また， (2) STM 検査成績は，時点を追うごとに成績が向上した。以上より伝導失語の経時的変化は発話４モダリティーに共通であり，音韻想起自体の障害から，音韻の選択・配列の障害を経て回復に至ると考えられた。また発話の改善と並行して STM 検査成績も上昇したことから，本症例の障害の根底には音韻の符号化 (選択・配列) 障害があり，現象面で STM の低下として観察された可能性があると考えた。
［目的］歩行障害を有する整形外科疾患患者に対し，体重免荷トレッドミル歩行トレーニング（Body Weight Support Treadmill Training：以下BWSTT）を施行し，その即時効果を明らかにすることを目的とした。［対象］歩行障害を有する整形外科疾患患者20名を対象とした。［方法］BWSTTを施行し，その前後の平地歩行における10 m歩行速度，歩幅，歩行中の歩きにくさ・重だるさ・疼痛の程度を比較した。［結果］BWSTT後では，10 m歩行速度の増大および歩幅の拡大がみとめられ，さらに歩行中の歩きにくさ・重だるさ・疼痛の程度はいずれの項目においても有意に低下していた。［結語］本研究により整形外科疾患患者を対象としたBWSTTでは即時効果があることが示唆された。
Therefore, the frame subtraction method could be applied to the evaluation of dynamic postural stability. Markerless systems are deemed useful in clinical practice.
The mechanisms of neuropathic pain developed following peripheral nerve injury have not been fully elucidated. As to recent findings, the one of the pivotal mechanisms is thought to be glutamate toxicity of spinal cord neurons due to repetitive nerve stimulation originating from the injured region. Therefore, a possible way to clarify is a direct observation of spinal glutamate release evoked by peripheral nerve injury. In the present study, we examined whether enhanced cerebrospinal fluid gluta
