The University of Osaka · 환경과학
Michihiko Ike 교수의 연구실은 환경 오염물질, 특히 비스페놀 유사 화합물(BPs)과 니온필놀계 화합물(NPEOs) 등의 생물학적 분해 거치는 메커니즘과 환경 영향을 중심으로 연구를 진행하고 있습니다. 주로 수생 환경에서의 생분해 가능성, 미생물에 의한 유기오염물질의 대사 경로 및 효소 체계를 규명하며, 오염물질의 완전한 분해 및 생물학적 제거 가능성을 탐색하고 있습니다. 특히 비스페놀 A, BPF, NPEO 유사 화합물의 분해 경로와 관련된 미생물 및 유전자 기반의 생물정화 기술 개발에 초점을 맞추고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
There is a group of compounds structurally similar to bisphenol-A (BPA), namely bisphenols (BPs), and some of them are considered to be able to partially replace BPA. In order to assess their biodegradability in the aquatic environment, a variety of BPs; BPA, bis(4-hydroxyphenyl)methane (BPF), bis(4-hydroxyphenyl)ethane (BPE), 2,2-bis(4-hydroxy-phenyl)butane (BPB), 2,2-bis(4- hydroxy-3-methylphenyl)propane (BPP), bis(4-hydroxyphenyl)sulfone (BPS), thiodiphenol (TDP) and 4,4'-dihydroxybenzophenon
Biodegradation of bisphenol-A (BPA), which is known as an estrogenic chemical, proceeds via complicated metabolic routes and leads to formation of several kinds of biodegradation products. Through the major route BPA can be completely mineralized; however, p-hydroxyacetophenone (p-HAP), p-hydroxybenzaldehyde (p-HBAL), and p-hydroxybenzoic acid (p-HBA) are transiently accumulated at relatively high concentrations. On the other hand, degradation of BPA through the minor route tends to cause the ac
Biodegradation potential of bisphenol A (BPA) in the aquatic environments was investigated using 3 activated sludge and 44 river water microcosms. The biodegradation potential was exhibited by most of the tested microcosms; 3 activated sludge and 40 river water microcosms. However, only 6 river water microcosms could completely mineralize BPA, and the others showed accumulation of common metabolites which were detected as 2 peaks according to a high-pressure liquid chromatograph. In total 19 BPA
Previously, we isolated a selenate- and arsenate-reducing bacterium, designated strain SF-1, from selenium-contaminated sediment and identified it as a novel species, Bacillus selenatarsenatis. B. selenatarsenatis strain SF-1 independently reduces selenate to selenite, arsenate to arsenite, and nitrate to nitrite by anaerobic respiration. To identify the genes involved in selenate reduction, 17 selenate reduction-defective mutant strains were isolated from a mutant library generated by random in
Three bacteria capable of utilizing bis(4-hydroxyphenyl)methane (bisphenol F [BPF]) as the sole carbon source were isolated from river water, and they all belonged to the family Sphingomonadaceae. One of the isolates, designated Sphingobium yanoikuyae strain FM-2, at an initial cell density of 0.01 (optical density at 600 nm) completely degraded 0.5 mM BPF within 9 h without any lag period under inductive conditions. Degradation assays of various bisphenols revealed that the BPF-metabolizing sys
The degradation kinetics of biotransformation products of nonylphenol polyethoxylates (NPEOs), nonylphenol (NP), nonylphenol monoethoxylate (NP1EO) and nonylphenoxy carboxylic acid (NP1EC), by ozonation and UV/TiO2 (ultraviolet photocatalytic degradation in the presence of titanium dioxide suspension as a catalyst) were investigated using lab-scale reactors. The degradation rate of NP by UV/TiO2 was the highest among the tested NPEOs metabolites, while NP1EC showed the lowest degradation rate. I
