Hokkaido University · 의학
미츠요시 타키구치 교수의 연구실은 수의학 분야에서의 염증 반응 및 간질환, 심장질환, 장내세균총 이상과 관련된 생물학적 마커를 중심으로 연구를 진행하고 있습니다. 특히 C-반응성단백질의 동물 모델 분리 및 특성 분석, 장내세균총 이상과 관련된 혈액 마커 탐색, 간섬유토판 및 심장 리모델링과의 연관성 등 정밀한 생물학적 기전 규명을 목표로 하고 있습니다. 초음파 기반의 비침습적 진단 기술 개발도 함께 진행되어, 임상적 적용 가능성이 높은 연구를 선도하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
C-reactive protein (CRP) was isolated from equine serum by use of calcium-dependent affinity chromatography conjugated pneumococcal C-polysaccharide, anion exchange chromatography, and gel filtration. It was identified as genuine CRP by its immunochemical cross-reactivity with anti-human CRP, its homology with human CRP in amino acid composition, and its pentameric structure as revealed by electron microscopy. Purified equine CRP had a molecular weight of approximately 118,000 and was composed o
Dogs that respond to ULFD management and are diagnosed with FR-PLE are expected to have a favorable prognosis. Clinical scores, specifically the CCECAI, could be useful for differentiating FR-PLE from IR-PLE or NR-PLE.
Plasma serine concentration might represent a novel maker of IBD in dogs.
Polypoid cystitis is a rare disease of the urinary bladder in dogs characterized by chronic inflammation, epithelial proliferation, and development of a polypoid mass or masses without histopathologic evidence of neoplasia. The ultrasonographic appearances of eight dogs with polypoid cystitis are described. Ultrasonography confirmed the presence of a bladder mass or masses in all patients. Ultrasonographic findings are mucosal projections and a polypoid to pedunculated mass of variable size and
The 2D-SWE may be useful for predicting the presence of hepatic fibrosis in dogs with hepatic disease.
These results indicate that vitamin D status is associated with the degree of cardiac remodeling, and the serum 25(OH)D concentration begins to decrease before the onset of heart failure in dogs with CVHD.
The PI and AUC can detect duodenal inflammation and hence are potentially useful for excluding a diagnosis of CIE.
A three-year-old, intact male, Siberian husky was evaluated for a two day history of dysuria. Sonographically there was an anechoic cyst-like structure in the urinary bladder. The abnormality appeared to be a 'cyst within a cyst', which is a characteristic ultrasonographic feature of ureterocele in humans. Ultrasonography may be a useful means of establishing a diagnosis of ureterocele in dogs.
CEUS parameters PI and AUC can provide useful information in differentiating acute pancreatitis from normal pancreas. Cerulein-induced AP was characterized by prolonged hyperechoic enhancement on CEUS.
