Ranjit De 교수

Carriers are equally important as drugs. They can substantially improve bioavailability of cargos and safeguard healthy cells from toxic effects of certain therapeutics. Recently, polymeric nanocarriers (PNCs) have achieved significant success in delivering drugs not only to cells but also to subcellular organelles. Variety of natural sources, availability of different synthetic routes, versatile molecular architectures, exploitable physicochemical properties, biocompatibility, and biodegradabil

Diets with naturally occuring chemopreventive agents are showing good potentials in serving dual purposes: firstly, for maintaining health, and secondly, for emerging as most puissant cost-effective strategy against chronic diseases like cancer. Genistein, one of the active soy isoflavone, is gaining attention due to its ability to impede carcinogenic processes by regulating wide range of associated molecules and signalling mechanisms. Epidemiologic and preclinical evidences suggest that suffici

Polyelectrolytes are polymers with repeating units of ionizable groups coupled with counterions. Recently, polyelectrolytes have drawn significant attention as highly promising macromolecular materials with potential for applications in almost every sector of our daily lives. Dyes are another class of chemical compounds that can interact with substrates and subsequently impart color through the selective absorption of electromagnetic radiation in the visible range. This overview begins with an i

Interactions in aqueous sodium polystyrenesulfonate (NaPSS) – NaCl solutions were studied conductometrically using a recent model based on scaling theory of polyions.

The delicate tertiary structure of proteins, their susceptibility to heat- and enzyme-induced irreversible denaturation, and their tendency to get accumulated at the cell membrane during uptake are daunting challenges in proteinaceous therapeutic delivery. Herein, a polyelectrolyte complex having encapsulated therapeutic protein has been designed on the surface of upconverting luminescent nanoparticles (NaYF₄:20%Yb³⁺,2%Er³⁺). This nanosized complex system has bee

Carbon quantum dots (CQDs) have gained tremendous attention due to their pertinence in diverse application fields. Herein, we report the application of nitrogen-doped CQDs (N-CQDs) for the sensitive detection of reactive oxygen species (ROS) <i>in vitro</i>. The N-CQDs were synthesized <i>via</i> a rapid, one-pot, cost-effective and environmentally friendly approach, and exhibited amphibious solubility in solvents with a wide range of relative polarities from 1 to 0.4. Spectroscopic and microsco

Silver nanorod (AgNR) array substrates were fabricated using an oblique angle thermal evaporation technique; their long-term stability, surface uniformity and reproducibility, which are primary requirements for their widespread realistic application and commercialization, were assessed using surface-enhanced Raman scattering (SERS) spectroscopy. The nanorod surfaces were functionalized using a series of organic thiols, which range from hydrophilic to hydrophobic, to mimic various conditions that

Abstract Precise measurements of the viscosities of solutions of sodium polystyrenesulfonate in water and in 2‐ethoxyethanol–water mixtures containing varying amounts of 2‐ethoxyethanol have been performed at 308.15, 313.15, 318.15 and 323.15 K. The intramolecular contributions to the reduced viscosities of the polyelectrolyte solutions were obtained through isoionic dilution maintaining the total ionic strengths of the solutions at polyelectrolyte concentrations of 0.0033, 0.0054 and 0.0080 eq