Samjin Choi
경희대학교 의공학교실 · 공학
Samjin Choi 교수의 연구실은 표면-enhanced 라만 분광법(SERS)을 핵심 기술로 활용하여 생체체액(예: 눈물, 양수)을 이용한 비침습적 질병 진단 기술을 개발하고 있습니다. 특히, 나노구조 플라스모닉 기반 센서와 다변량 통계, 머신러닝을 융합해 암, 출산 전 질환, 바이러스성 결막염 등에 대한 고감도·고신뢰도 진단을 목표로 하고 있습니다. 연구는 임상 응용에 적합한 재현성과 균일성을 확보한 소재 설계와 센서 플랫폼 개발에 초점을 맞추고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Surface-enhanced Raman scattering (SERS) is an ultrasensitive molecular screening technique with greatly enhanced Raman scattering signals from trace amounts of analytes near plasmonic nanostructures. However, research on the development of a sensor that balances signal enhancement, reproducibility, and uniformity has not yet been proposed for practical applications. In this study, we demonstrate the potential of the practical application for detecting or predicting asymptomatic breast cancer fr
We report the development of a surface-enhanced Raman spectroscopy sensor chip by decorating gold nanoparticles (AuNPs) on ZnO nanorod (ZnO NR) arrays vertically grown on cellulose paper (C). We show that these chips can enhance the Raman signal by 1.25 × 10<sup>7</sup> with an excellent reproducibility of <6%. We show that we can measure trace amounts of human amniotic fluids of patients with subclinical intra-amniotic infection (IAI) and preterm delivery (PTD) using the chip in combination wit
The formation of spinel oxide has been investigated by chemically extracting lithium with the oxidizing agent from three samples of that were synthesized at 400, 600, and 800°C to obtain followed by heat-treatment at 200°C. The samples have been characterized by X-ray diffraction, atomic absorption spectroscopy, and a redox titration to determine the oxygen content. While the sample obtained from the crystallizes in the normal cubic spinel structure with a cation distribution of that obtained fr
Cell culture and polymerase chain reaction are currently regarded as the gold standard for adenoviral conjunctivitis diagnosis. They maximize sensitivity and specificity but require several days to 3 weeks to get the results. The aim of this study is to determine the potential of Raman spectroscopy as a stand-alone analytical tool for clinical diagnosis of adenoviral conjunctivitis using human tear fluids. A drop-coating deposition surface enhanced Raman scattering (DCD-SERS) method was identifi
spinel oxides with 0.36 < δ < 0.46 were synthesized by oxidation of aqueous with hydrogen peroxide or lithium peroxide in the presence of lithium carbonate or lithium hydroxide followed by firing the precursor in air at 300–400°C spinel is metastable and disproportionates at about 500°C to give a lithium‐rich spinel and . The disproportionation temperature and the amount of impurity formed depended on the synthesis procedure and raw materials used. Use of lithium peroxide and lithium hydroxide i
