Sang Wook Kang
경희대학교 의과대학·의학전문대학원 · 의학
강상욱 교수의 연구실은 산화 스트레스와 DNA 손상 복구와 관련된 유전자 다형성(예: SOD2, hOGG1, ACE)이 암 및 만성 폐질환과 연관되는지에 대한 메타분석을 중심으로, 특히 유전자 변이가 질병 발생에 미치는 영향을 정량적으로 평가하는 데 초점을 맞추고 있습니다. 또한, 천연물 유래 화합물(예: 피노레신올 글루코시드, TMARg)이 뼈 형성 및 세포 분화에 미치는 작용 기전을 밝혀내는 생물학적 기전 연구도 진행 중입니다. 이는 산화 방어 효소, DNA 복구 효소, 그리고 천연물 기반 치료제 개발을 연결하는 다학제적 접근을 특징으로 합니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
In this study, we show for the first time that potassium fluoride (KF) can be utilized as a carrier for facilitated CO2 transport. A polymer electrolyte membrane was prepared by incorporating KF through coordinate covalent bonding with the amide groups of poly(vinylpyrrolidone) (PVP). The resulting PVP/KF electrolyte membrane showed enhanced CO2 separation performance compared with neat PVP. The selectivity ratio CO2/N2 increased to 4.1 with a CO2 permeance of 28 GPU. This enhanced separation pe
With increasing technological demand for portable electronic and photovoltaic devices, it has become critical to ensure the electrical and mechano-electric reliability of electrodes in such devices. However, the limited flexibility and high processing costs of traditional electrodes based on indium tin oxide undermine their application in flexible devices. Among various alternative materials for flexible electrodes, such as metallic/carbon nanowires or meshes, silver nanowire (Ag NW) networks ar
CD137 (4-1BB) is a T-cell costimulatory molecule, and agonstic CD137 antibodies are currently being evaluated in the clinic as cancer immunotherapy. Recently, it was found that CD137<sup>-/-</sup> mice or mice injected with agonistic anti-CD137 antibodies exhibit heightened antitumor responses, contrary to expectations based on other knowledge of CD137 function. Here, we report findings related to reverse signaling by CD137 ligand (CD137L) in antigen-presenting dendritic cells (DC) in tumors tha
Superoxide dismutase, one of the antioxidant enzymes, plays an important role in defense against reactive oxygen species. Many previous studies reported the association between SOD2 polymorphism and the cancer risk but the results were divergent. Therefore, we performed a meta-analysis to investigate the association between SOD2 polymorphism and the cancer susceptibility. We searched in Electronic database including Pubmed, Embase, google of scholar, and Korean Studies Information Service System
A theoretical model is made to investigate the coupling effects of the trim and air gap on the frequency response characteristics of a passenger compartment. With the model, a parametric study is carried out to understand the relation between the acoustic response of the cavity and the design variables associated with the roof, trim, and air gap between the two. The validity of theoretical formulations is verified through a comparison between the theoretical results and the finite element analys
