Sang‐Chol Lee
성균관대학교 약학대학 · 의학
이 교수의 연구실은 뇌혈관질환과 심장질환의 조기 진단 및 예후 예측에 초점을 맞추고 있습니다. 특히 뇌경색의 무증상 병변(소뇌경색)의 유병율과 위험인자 분석, 그리고 비정상적인 심장기능 이상을 가진 환자에서의 심장기능 평가 및 심장성 정신병리 위험 예측에 대한 연구를 진행하고 있습니다. 특히 심장기능의 정량적 평가 지표인 LV-GLS를 활용한 심장마비 예측 연구로 임상적 실용성과 예후 예측 정확도를 높이고자 합니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Cerebrovascular disease is a major cause of death and disability in adults. Silent cerebral infarction (SCI) portends more severe cerebral infarctions or may lead to insidious progressive brain damage resulting in vascular dementia. This study was designed to evaluate the prevalence and risk factors of SCI in an apparently normal adult population. Nine hundred ninety-four consecutive symptom-free adults (mean age 49.0+/-7.7; men:women 830:164) who underwent brain magnetic resonance imaging at th
ApHCM showed a relatively small burden of myocardial fibrosis and less severe diastolic dysfunction and subsequently more favourable clinical manifestations in comparison with other HCMs. This may be one explanation of why most patients with ApHCM show a benign course of disease compared with non-ApHCM.
LV-GLS is an important prognosticator in patients with HCM and provides additional information to established risk stratification strategies for predicting SCD.
Dry cough is the most common limiting factor of ACE inhibitor (ACEI) use. Generation of NO, a proinflammatory substance on bronchial epithelial cells, is increased by ACEI. Using a randomized, double-blind, placebo-controlled trial, we tested the hypothesis that supplementing iron, an inhibitor of NO synthase, may reduce the cough associated with ACEI use. The subjects were 19 patients who had developed ACEI-induced cough. After a 2-week observation period, they were randomized to a daily mornin
