Nagoya University · 의학
Satoshi Yanagisawa 교수의 연구실은 심부전을 동반한 심방세동 환자를 대상으로 한 치료 전략과 생체마커와 신경조절 기전을 연계한 심장 리모델링 연구에 초점을 맞추고 있습니다. 특히 레이저 치료 후 심장 기능 회복과 부정맥 재발 예측을 위한 혈액학적 지표(RDW), 뇌뇌내피질호르몬(BNP), 자율신경조절(HRV, EAT)의 역할을 심층적으로 분석하고 있습니다. 또한 CRT(심실세동 조절)의 반응성과 항응고 치료의 출혈 위험도를 고려한 개인 맞춤형 치료 전략 개발에도 기여하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
High RDW is an independent predictor for the recurrence of AF and major adverse events in patients with HF after catheter ablation. RDW is a potential noninvasive marker in AF patients complicated with HF. (Circ J 2016; 80: 627-638).
The periprocedural bleeding risk during the use of uninterrupted oral anticoagulants was higher in the elderly group than in the younger group. This area needs more attention for these patients in whom caution is required.
The reverse dynamics of PWD after initial shortening directly following ablation were significantly associated with PV reconnection.
Plasma BNP levels decreased significantly with successful catheter ablation of AF in patients with impaired LVEF. The decrease in BNP levels might be associated with early recovery of cardiac function and subsequent maintenance of sinus rhythm at follow-up.
Greater response to biventricular pacing occurs more frequently in patients with consistent right ventricular pacing, lack of prior history of ventricular arrhythmia, and smaller LAD. An association between patient background characteristics and a super-response to CRT was also identified.
Changes in HRV parameters following ablation were similarly observed in both the groups. EAT volume on the LA-PV junction is helpful for interpretation of VR occurrence and ANS modulation.
