Se Eun Park
성균관대학교 의과대학 · 의학
Se Eun Park 교수의 연구실은 당뇨병의 조기 진단과 병태생리 기전 규명을 목표로 하며, 인슐린 저항성과 관련된 생체마커(예: 아디포카인, 미오카인, 헤파토카인, 유뇨 ACE2, RBP4)의 역할을 중심으로 연구를 진행하고 있습니다. 특히 신장 기능 이상과 연관된 생체지표 탐색과 자율신경 조절 이상이 당뇨 발생에 미치는 영향에 대한 기초 및 임상 연구를 융합적으로 수행하고 있습니다. 이는 조기 선별 및 개인 맞춤형 관리 전략 개발에 기여할 잠재력을 지닙니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Insulin resistance in insulin target tissues including liver, skeletal muscle and adipose tissue is an early step in the progression towards type 2 diabetes. Accurate diagnostic parameters reflective of insulin resistance are essential. Longstanding tests for fasting blood glucose and HbA1c are useful and although the hyperinsulinemic euglycemic clamp remains a "gold standard" for accurately determining insulin resistance, it cannot be implemented on a routine basis. The study of adipokines, and
Diabetes mellitus remains highly prevalent among Korean adults, with significant gaps in integrated glycemic, blood pressure, and lipid control. Older adults with diabetes show higher awareness and treatment rates but limited integrated management outcomes. Young adults with diabetes bear a significant burden of obesity and comorbidities, alongside low awareness and treatment rates. Therefore, early intervention programs, education, and strategies tailored to younger populations are urgently req
Our data suggest that the urinary ACE2 level is closely associated with T2DM and is an independent risk factor for microalbuminuria.
Urinary RBP4 concentrations were elevated in patients with dysregulation of glucose metabolism and were related to various cardiometabolic risk factors including insulin resistance, inflammation, and microalbuminuria.
Abnormal HRV, especially decreased vagal activity and deviation in sympathovagal imbalance to sympathetic activity, might precede incident diabetes.
