연세대학교 · 의학
Seng Chan You 교수의 연구실은 심혈관계 질환의 예방 및 조기 진단에 중점을 두고 있으며, 특히 혈전성 질환에서의 항혈소판 치료제 효과, 간섬유화 및 비알코올성간지방증의 동맥경화 위험과의 연관성, 그리고 아시아 인구 특화의 임상 연구를 중심으로 진행되고 있습니다. 고해상도 영상 및 생체정보를 활용한 위험도 평가 모델 개발과 함께, 대규모 건강 데이터 기반의 국제 공동 연구 네트워크 구축에도 기여하고 있습니다. 특히 한국의 전국 대상자 데이터를 오픈소스 데이터 모델로 변환하여 글로벌 임상 연구에 기여하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Among patients with ACS who underwent PCI in routine clinical practice, ticagrelor, compared with clopidogrel, was not associated with significant difference in the risk of NACE at 12 months. Because the possibility of unmeasured confounders cannot be excluded, further research is needed to determine whether ticagrelor is more effective than clopidogrel in this setting.
The prevalence of significant liver fibrosis assessed using TE was 6.9% in apparently healthy subjects. High BMI, high ALT, thicker carotid IMT, and higher numbers of calcified carotid plaques were independently associated with the presence of significant liver fibrosis.
Higher CAC score was independently correlated with LS values in subjects with NAFLD. However, it should be further investigated whether TE can be incorporated into a screening tool to identify the high-risk population for coronary artery disease.
It is increasingly necessary to generate medical evidence applicable to Asian people compared to those in Western countries. Observational Health Data Sciences a Informatics (OHDSI) is an international collaborative which aims to facilitate generating high-quality evidence via creating and applying open-source data analytic solutions to a large network of health databases across countries. We aimed to incorporate Korean nationwide cohort data into the OHDSI network by converting the national sam
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This study aimed to investigate the incidence, predictors, and clinical outcomes of cardiac tamponade after heart valve surgery. A total of 556 patients who underwent heart valve surgery in a single tertiary center between January 2010 and March 2012 were studied. All patients underwent transthoracic echocardiography (TTE) about 5 days after surgery and TTE was repeated regularly. Patients with suspected acute pericardial hemorrhage were excluded. Cardiac tamponade occurred in twenty-four (4.3%)
