Seong Jin Jo
서울대학교 피부과학교실 · 의학
Seong Jin Jo 교수의 연구실은 피부질환 치료 및 피부 생물학의 기초 메커니즘을 중심으로 다학제적 연구를 수행하고 있습니다. 특히 임상적 응용에 초점을 맞춘 혁신적 치료 전략으로는 아교세포 유래 혈장(ADSC-CM)을 이용한 여성형 탈모 치료, 그리고 난방광선(nbUVB) 치료의 안전성 평가 등이 있습니다. 또한 원격 진료 기술인 텔레더마토로지의 진단 정확도 향상과 전통 발효식품인 된장의 숙성 과정에서의 생리활성 성분 변화에 대한 분석을 통해 의학적 응용 가능성을 탐색하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
The application of ADSC-CM is a potential treatment option for FPHL.
Narrowband ultraviolet B (nbUVB) phototherapy is used around the world for the treatment of various skin diseases. However, the carcinogenic risk associated with nbUVB treatment in patients with skin phototypes III-V has not been studied. This retrospective study compared the incidence of skin cancer in Korean patients with skin phototypes III-V treated with nbUVB with that in a control Korean population. A total of 445 nbUVB-treated patients were followed for 1,274 person-years (mean follow-up
We evaluated the diagnostic accuracy of teleconsultations for skin diseases common in the army using a smartphone multimedia messaging service (MMS). Images of skin lesions were obtained from 100 army patients using digital cameras built into smartphones. Three remotely located dermatologists received the dermatology images and associated clinical information via the MMS. The teledermatologists' diagnoses were compared with those obtained from face-to-face examinations. The three most common dia
본 연구는 전통된장의 숙성기간에 따라 일반성분, pH, 색도, 지방산, 아미노산, γ-aminobutyric acid(GABA) 및 isoflavone의 변화에 대해 연구하였다. 실험에 사용한 전통 된장은 강원도 서원 농협에서 제조한 된장으로 숙성기간이 1, 3, 5, 7 및 10년이 경과된 된장을 사용하였으며, 대조군으로는 숙성시키지 않은 된장을 사용하였다. 일반성분 중 수분의 경우 3년째까지 일시적으로 증가하였다가 그 이후에는 감소하는 경향을 나타내었으며, pH와 색도는 숙성기간이 증가함에 따라 감소하였다. 지방산의 경우 숙성기간에 따른 유의적인 차이는 없었으나 불포화지방산의 비율이 60% 이상을 차지하였다. 아미노산 또한 유의적인 차이는 없었으나 GABA의 전구체인 glutamic acid가 숙성기간이 증가함에 따라 유의적으로 감소하는 것으로 나타났다. 대조군 시료의 경우 GABA의 함량을 분석한 결과 24.9 mg/kg이었으나, 숙성기간이 증가함에 따라 43.8, 120.6,
A new strategy for control of the in-plane orientation of pentacene is introduced using nanometer-scale periodic groove patterns as an alignment layer. Compared to pentacene films that are not aligned, an enhanced field effect mobility of 1.67 cm2 V−1 s−1 has been achieved when the optimal π-orbital overlap direction is parallel to the direction of the current flow. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2089/2008/adma200701076_s
We found no clinical evidence to support the use of pyridoxine supplements to prevent HFS during chemotherapy.
Given that the pulse duration, fluence, and epidermal cooling were identical, the 805-nm LPDL at the three times larger spot size showed an efficacy improvement of 29.5% in axillary hair removal without serious adverse events.
The effects of tetrafluoromethane (CF4) plasma treatment of indium-tin-oxide (ITO) anode on indium diffusion into a poly(3,4-ethylene dioxythiophene):poly(styrene sulphonate) (PEDOT:PSS) layer were studied. Auger electron spectroscopy (AES) depth profile showed that 0.2at.% indium was present in the PEDOT:PSS layer when ITO was not plasma treated. The plasma treatment of ITO increased the indium concentration to ∼6at.%. The increase in indium can be explained by an oxygen deficiency in the CF4 p
The results of this cross-sectional study suggest that patients with PPP have an overlapping comorbidity profile with patients with psoriasis vulgaris but not patients with pompholyx. However, the risks of comorbidities among patients with PPP may be substantially different from those among patients with psoriasis vulgaris.
This clinical trial revealed that APHG-1001, which contains an extract of P. lobata, could prevent the development of new gray hair without any remarkable adverse effects. Thus, it can be considered as a viable treatment option for the prevention of gray hair.
In this study, cells from the stromal vascular fraction of human subcutaneous tissues were induced to differentiate toward adipose cells in vitro for 2 weeks. During adipogenic differentiation, we followed the chronological changes in their morphology with Coherent anti-Stokes Raman scattering (CARS) microscopy and checked the PPAR-γ and UCP-1 expression with RT-PCR. On day 4 after inducing adipogenic differentiation, CARS imaging showed multiple small lipid droplets (LD) distributed peripherall
This study shows that pigmentation induced by narrow-band UVB phototherapy increases continuously during the therapy and that recovery requires 10 weeks or more.
Acrodermatitis continua of Hallopeau (ACH) is a rare chronic pustular eruption that predominantly involves the fingertips. The characterization of this disease has been confused. Some have considered it as a separate entity while others as a variant of pustular psoriasis. The presented patient simultaneously had ACH and joint lesions which were diagnosed as psoriatic arthritis. We believe that because ACH may be accompanied by psoriatic arthritis, as in this case, it could be evidence that it is