慶應義塾大学 · Medicine
Shun Kohsaka 교수의 연구실은 심부전, 심근경색 및 심장마비와 관련된 혈역학적 및 생물학적 기전을 규명하는 데 초점을 맞추고 있습니다. 특히 심부전 환자의 예후 예측 모델 개선을 위해 생체마커와 임상 지표를 융합한 평가 방법을 개발하고 있으며, 심장의 전도 및 기능 평가에 있어 ECG 및 에코카디오그래피의 임상적 응용 가능성을 탐색하고 있습니다. 또한 우심실 경색과 같은 복잡한 심혈관계 합병증의 조기 진단 및 경과 관리 전략 개발에도 기여하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Almost one fifth of patients with acute myocardial infarction complicated by CS showed clinical signs of severe systemic inflammation, and those who were culture-positive for sepsis had twice the risk of death. The observation of lower SVR at the onset of shock in patients who subsequently had culture-positive systemic inflammation suggests that inappropriate vasodilation may play an important role in the pathogenesis and persistence of shock and in the risk of infection.
The original MAGGIC score performed modestly in Japanese patients, but the addition of discharge BNP level enhanced model performance. The addition of objective biomarkers may result in effective modification of preexisting internationally recognized risk models and aid in multinational comparisons of heart failure patients' outcomes.
ECG-LAA can supplement 2D echocardiography in assessing the risk of ischemic stroke, especially in subjects with increased left ventricular mass.
In recent years, right ventricular (RV) infarction seems to be underdiagnosed in most cases of acute myocardial ischaemia despite its frequent association with inferior-wall and, occasionally, anterior-wall myocardial infarction (MI). However, its initial management is drastically different from that of left ventricular MI, and studies have indicated that RV infarction remains associated with significant morbidity and mortality, even in the mechanical reperfusion era. The pathophysiology of RV i
