홍순철 교수

Estrogen deficiency resulted in increased TNF-alpha levels. Serum leptin levels correlated positively with estrogen levels in premenopausal women. However, the increase in obesity in postmenopausal women increased leptin, which increases insulin resistance.

Although there is accumulating evidence regarding the additional protective effect of folic acid against adverse pregnancy outcomes other than neural tube defects, these effects have not been elucidated in detail. We evaluated whether folic acid supplementation is associated with favorable maternal and fetal outcomes. This was a secondary analysis of 215 pregnant women who were enrolled in our prior study. With additional data from telephone interviews regarding prenatal folic acid supplementati

The purpose of this study is to evaluate the relationship between maternal and/or cord blood folate/homocysteine concentrations and adverse pregnancy outcomes. The study population included a random sample of singleton pregnant women in whom we measured total homocysteine and folic acid in maternal or cord blood at deliveries. A total of 227 pregnant women were enrolled. The concentration of folate in maternal blood tended to be significantly lower in pre-term birth than in full-term delivery gr

CD44v6 may be involved in stromal invasion of early squamous cervical carcinomas and in the cellular differentiation of endometrial cancer. In addition, it may be useful for early diagnosis of endometrial cancer.

A large intrauterine cyst containing a heterogenous mass was found by ultrasound in the placenta of a 35-year-old gravida 2 para 1 woman. The cyst, measuring 10.9 x 10.1 cm with a heterogenous mass shadow, was attached near the placental cord insertion site. The woman delivered a healthy female baby weighing 3,330 g by cesarean section without complication. A histopathological examination revealed that the lesion was a subchorionic cyst and contained an internal hematoma. Large subchorionic cyst

This study aimed to determine the correlation between the placental thickness-to-estimated foetal weight ratio on midterm ultrasonography and small-for-gestational-age (SGA) infants. In this retrospective study, the placental thickness at the umbilical cord insertion site was measured and adjusted for foetal body weight at 18-24 weeks gestation. Investigators compared the data of women who delivered SGA infants (birth weight <10th percentile) with those of women who delivered non-SGA infants. Am

The results of this meta-analysis suggest that administration of preventive progestogen treatment to women at risk for preterm birth does not appear to negatively affect neonatal mortality in single or multiple pregnancies regardless of the route of administration.

S ince the 1980's, prenatal care for pregnant women and their babies has improved maternal and neonatal health. However, despite prenatal care, the rate of some complications, such as major fetal anomalies, preterm labor, and low birth weight have not improved. Only 10.3% of Korean women of childbearing age take folic acid supplementation and approximately 14% still consume alcohol during pregnancy. Because in Korea about 50% of pregnancies are unintended, those women have higher exposure rates

본 연구는 임부를 대상으로 임신 전 관리 실태와 임신 전 관리 실시 여부에 영향하는 요인을 분석하여, 향후 임신 전 관리 지원 프로그램 개발 및 정책 방향 제시를 위한 기초자료 제공에 목적이 있다. 본 연구의 자료수집은 대학병원과 산부인과 전문병원 외래 및 마터너티스쿨 교육에 참여한 임부를 편의추출하여 자가기입식 설문조사 방식으로 이루어졌다. 본 연구 대상자인 임부들은 우리나라 전체 임부 특성과 유사하게 임신 초기부터 임신을 인지하고 산전관리를 규칙적으로 받고 있었으나, 흡연, 음주 등 생활습관관리가 필요함을 확인할 수 있었다. 임부 중 유산 경험이 있는 대상자는 22.3%, 임신 전 유질환자도 11.4% 로 되는 것으로 나타나, 출산율을 높이기 위한 방안의일환으로 유산을 예방하고 감소시킬 수 있는 다각도의방안 모색과 유질환자 대상 체계적 임신 전 관리 프로그램 실시가 절실함을 확인하였다. 임부들의 임신 전 관리에 대한 인지도와 필요성에 대한 인식은 높으나, 실질적인 임신 전 관리

Since the 1980’s, prenatal care for pregnant women and their babies has improved maternal and neonatal health. However, despite prenatal care, the rate of some complications, such as major fetal anomalies, preterm labor, and low birth weight have not improved. Only 10.3% of Korean women of childbearing age take folic acid supplementation and approximately 14% still consume alcohol during pregnancy. Because in Korea about 50% of pregnancies are unintended,those women have higher exposure rates to