Sujung Yoon
이화여자대학교 뇌·인지과학부 · 신경과학
Sujung Yoon 교수의 연구실은 뇌의 신경가소성과 구조적 기능 이상이 관련된 정신질환, 특히 외상 후 스트레스 장애(PTSD), 양극성 장애, 약물 남용 등에서의 신경염증 및 구조적 뇌망막 변화를 중심으로 연구를 진행하고 있습니다. 특히 뇌영상 기반 신경가소성, BDNF 유전자 다형성과 백질 구조망의 상호관계, 청소년기 중성 약물 사용이 뇌 대사 및 인지기능에 미치는 영향을 다각도로 분석하고 있습니다. 이는 뇌의 기능적·구조적 변화를 이해하고, 정신질환의 생물학적 기반을 규명하는 데 초점을 맞추고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Post-traumatic stress disorder (PTSD) is a chronic condition characterized by symptoms of physiological and psychosocial burden. While growing research demonstrated signs of inflammation in PTSD, specific biomarkers that may be representative of PTSD such as the detailed neural correlates underlying the inflammatory responses in relation to trauma exposure are seldom discussed. Here, we review recent studies that explored alterations in key inflammatory markers in PTSD, as well as neuroimaging-b
This systematic review suggests disruption in the functional activity of large-scale brain networks at rest as well as during a task stimuli in bipolar disorder. Disrupted intra- and internetwork functional connectivity that are also associated with clinical symptoms suggest altered functional connectivity of and between large-scale networks plays an important role in the pathophysiology of bipolar disorder.
Val66Met, a naturally occurring polymorphism in the human brain-derived neurotrophic factor (BDNF) gene resulting in a valine (Val) to methionine (Met) substitution at codon 66, plays an important role in neuroplasticity. While the effect of the BDNF Val66Met polymorphism on local brain structures has previously been examined, its impact on the configuration of the graph-based white matter structural networks is yet to be investigated. In the current study, we assessed the effect of the BDNF pol
The adolescent brain, with ongoing prefrontal maturation, may be more vulnerable to drug use-related neurotoxic changes as compared to the adult brain. We investigated whether the use of methamphetamine (MA), a highly addictive psychostimulant, during adolescence affect metabolic and cognitive functions of the anterior cingulate cortex (ACC). In adolescent MA users (n = 44) and healthy adolescents (n = 53), the levels of N-acetyl aspartate (NAA), a neuronal marker, were examined in the ACC using
