Sun Ju Chang
서울대학교 간호학과 · 의학
Sun Ju Chang 교수의 연구실은 신경발달 및 신경재생 분야에서 활동하며, 특히 신경세포의 축삭 확장과 신경성장 인자 작용 메커니즘을 규명하는 데 초점을 맞추고 있습니다. 신경세포 표면 단백질인 G4 분자와 NCAM 등의 역할을 분석하여 축삭 성장 조절 기전을 밝혀내고 있으며, e-Health 리터러시 및 만성질환 관리에 기여하는 행동간호 전략 개발에도 기여하고 있습니다. 특히 신경세포의 신호전달 및 세포 간 상호작용 메커니즘을 기반으로 한 신경재생 및 신경질환 치료 전략 개발을 추구하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
We have developed an in vitro assay which measures the ability of growth cones to extend on an axonal substrate. Neurite lengths were compared in the presence or absence of monovalent antibodies against specific neural cell surface glycoproteins. Fab fragments of antibodies against the neural cell adhesion molecule, NCAM, have an insignificant effect on the lengths of neurites elongating on either an axonal substrate or a laminin substrate. Fab fragments of polyclonal antibodies against two new
Purpose: This study systematically reviewed research on behavioral interventions based on the information-motivation-behavioral skills (IMB) model to investigate specific intervention strategies that focus on information, motivation, and behavioral skills and to evaluate their effectiveness for people with chronic diseases. Methods: A systematic review was conducted in accordance with the guidelines of both the National Evidence-based Healthcare Collaborating Agency and Im and Chang. A literatur
Purpose: The purpose of this study was to cross-culturally adapt the eHealth Literacy Scale into Korean (KeHEALS) and evaluate its reliability and validity. Methods: The cross-cultural adaptation of the KeHEALS was conducted according to the World Health Organization's guideline. To evaluate the reliability and validity, the data of 397 participants (210 young adults and 187 older adults) were collected from 2017 November to 2018 February. An online survey was conducted with young adult
This review provides evidence for AAT as an intervention in the physiological, psychosocial, cognitive, and behavioral domains of older adults. When planning interventions for older adults, nurses should consider intended health outcomes, appropriate therapeutic animals, and the consequent intervention contents.
The findings can help healthcare providers choose a suitable measure of eHealth literacy when working with older adults.
The chick G4 molecule is a cell surface glycoprotein which is a member of the L1/NILE/NgCAM/8D9 group of neural cell adhesion molecules. Polyclonal antisera against G4 have been shown to decrease sympathetic neurite outgrowth on sympathetic axons and to de-bundle retinal axons growing on a tectal membrane substrate. We have extended the specificity of these results by showing that a panel of monoclonal antibodies against G4 is also effective in reducing sympathetic neurite outgrowth on sympathet
This review demonstrates that internet-delivered cognitive behavioral therapy could be a cost-effective intervention for improving symptoms and the quality of life in patients with irritable bowel syndrome. However, studies are still insufficient regarding the use of internet-delivered cognitive behavioral therapy in these patients; therefore, more high-quality studies are required in the future.
Nurses who take care of multiethnic groups of midlife women who experience menopausal symptoms should be aware of diverse types of women's physical activities within the cultural context.
Health care providers should be aware of the effects of health literacy and self-care behaviours on health-related quality of life and consider the factors associated with quality of life when they take care of older persons with lung cancer receiving chemotherapy.
This review aimed to provide information on ways to improve eHealth literacy in older adults by assessing current studies examining eHealth literacy. To achieve the aim, this review focused on what theories or theoretical frameworks were used in the studies, what factors were related to eHealth literacy, and what outcome variables were used in eHealth literacy interventions for older adults. Five electronic databases were searched to identify eligible studies. The Cochrane Handbook for Systemati
Pain catastrophizing is a notable concept associated with change in chronic pain interference and depression. Sleep quality is also one of the important factors affecting geriatric depression. This study examined the mediating effects of chronic pain interference and sleep quality on the relationship between pain catastrophizing and depression. This study is a secondary data analysis that analyzed a total of 138 older Korean adults with chronic pain. The participants were selected from a single
The application of the current theory-based methodology can improve the quality of research in eHealth literacy. Additionally, various interventions should be developed and continuously applied to improve eHealth literacy among older adults.