Sun Young Kim
경희대학교 의예과 · 의학
Sun Young Kim 교수의 연구실은 노인 건강과 퇴행성 질환의 생체지표 및 생물학적 기전을 중심으로 연구를 진행하고 있습니다. 주로 체형 지표인 복부 둘레(CC)와 근육량(ASM)이 노인의 신체 기능 및 골다골증 위험과 어떻게 연관되어 있는지 규명하며, 한국 노인 인구를 대상으로 한 생체 영상 및 생화학적 분석을 기반으로 한 정밀의료 기반의 생체지표 개발에 주력하고 있습니다. 또한 전통 약재의 항혈전 작용 메커니즘과 유기합성 반응을 통한 기능성 고리 구조 합성에도 관심을 기울이고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
The optimal cut-off values of CC for low MM are 35 cm for males and 33 cm for females. Lower CC based on these cut-off values is related with poor physical function. CC may be also a good indicator of sarcopenia in Korean elderly.
The purpose of this study was to predict osteoporosis risk as decreasing muscle mass and to declare the cut-off value of low muscle mass in an elderly Korean population. This study was based on data from the 2008-2010 Korea National Health and Nutritional Examination Surveys (KNHANES). The subjects included 1,308 men and 1,171 women over 65 yr. Bone mineral density (BMD) and appendicular skeletal muscle (ASM) were measured by dual energy X-ray absorptiometry (DXA), and appendicular skeletal musc
Choose your catalyst wisely: Depending on the position of the cyclopropyl substituent on the bicyclo[4.1.0]hept-2-ene substrate, a different rhodium complex was used to catalyze the title reaction, which leads to bicyclic dienones in reasonable to excellent yields (see scheme). The products contain a highly substituted seven-membered ring with useful functionality for further manipulation. R1=H, Me; R2=H, Me, Ph; R3=Me, Et; X=NR, O.
Cinnamomum cassia is a well-known traditional medicine for improvement of blood circulation. An extract of this plant showed both platelet anti-aggregation and blood anti-coagulation effects in preliminary testing. Among the 13 compounds obtained from this plant, eugenol (2), amygdalactone (4), cinnamic alcohol (5), 2-hydroxycinnamaldehyde (7), 2-methoxycinnamaldehyde (8), and coniferaldehyde (9) showed 1.5-73-fold greater inhibitory effects than acetylsalicylic acid (ASA) on arachidonic acid (A
Enyne-enyne-o: Tandem cycloisomerization of dienynes catalyzed by platinum dichloride and subsequent Cope rearrangement affords bicyclic rings (see scheme; Z=NTs, O, CH2), such as bicyclo[3.2.2]nonadienes 1 or tetrahydrocyclohepta[c]pyrans and -pyridines 2, in high yields.
Rapid, spatially compatible, localized thinning of the retinal nerve fiber layer after the first detected DH was shown by Stratus OCT.
