Sung Kwan Shin
연세대학교 의과대학 의학과 · 의학
서강신 교수의 연구실은 바이러스와 암 간의 연관성에 초점을 맞춘 전임상 암 생물학 연구를 수행하고 있습니다. 특히 허브-크리스티안 바이러스(JCV)의 T-항원 발현이 위암에서 관찰된다는 점을 최초로 규명하며 바이러스가 위암 발생에 기여할 수 있음을 제시했습니다. 이는 바이러스 유전자가 암 발생 메커니즘에 미치는 영향을 규명하는 데 기여하는 핵심 연구입니다. 향후 바이러스 기반 암 치료 전략 개발에도 기여할 잠재력을 지닙니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Endoscopic resection is a safe and effective modality for treating well-differentiated rectal carcinoids smaller than 10 mm in diameter. Discrepancies were observed between CR-E and CR-P. The risk factors for metastasis were tumor size, increased mitotic rate, and lymphovascular invasion.
One of the most important prognostic factors in esophageal carcinoma is lymph node metastasis, and in particular, the number of affected lymph nodes, which influences long-term outcomes. The esophageal lymphatic system is connected longitudinally and transversally; thus, the pattern of lymph node metastases is very complex. Early esophageal cancer frequently exhibits skipped metastasis, and minimal surgery using sentinel node navigation cannot be performed. In Korea, most esophageal cancer cases
With unique clinicopathological features, intestinal-type MSI-H gastric cancers are associated with good prognosis and can be classified as a different subset of gastric cancers.
To the authors' knowledge, this is the first demonstration of the presence of JCV T-Ag expression in human gastric cancers. These findings suggest a possible role for this polyomavirus in gastric carcinogenesis.
The polaprezinc plus PPI treatment showed noninferiority to rebamipide plus PPI treatment in the ulcer healing rate at 4 weeks after ESD.
ESD can be considered an effective and safe alternative therapeutic and diagnostic tool for gastric lesions in cases where the forceps biopsy pathology is discrepant from the endoscopic findings. The overall final neoplastic diagnosis rate after ESD was 64.5%, and ESD should be performed for lesions with red coloration and friability.
Our results indicate that remimazolam is a safe and useful sedative for upper gastrointestinal endoscopy.