Sung‐Hyuk Sunwoo 교수

High-performance wearable and implantable devices capable of recording physiological signals and delivering appropriate therapeutics in real time are playing a pivotal role in revolutionizing personalized healthcare. However, the mechanical and biochemical mismatches between rigid, inorganic devices and soft, organic human tissues cause significant trouble, including skin irritation, tissue damage, compromised signal-to-noise ratios, and limited service time. As a result, profuse research effort

Mechanically soft metallic nanocomposites have gained much attention as a key material for intrinsically stretchable biointegrated devices. However, it has been challenging to develop a stretchable conductive nanocomposite with all the desired material characteristics including high conductivity, high stretchability, low cytotoxicity, and low impedance. Here, we present a material strategy for the stretchable conductive nanocomposite, particularly emphasizing low impedance, by combining silver-g

Abstract Cardiac resynchronization therapy (CRT) presents effective means to modulate cardiac conduction and related functions in heart failure patients. However, the conventional CRT delivers electric current at only two points on the heart, therefore, it is unable to provide comprehensive electrical support to the heart. Additionally, the CRT‐device structure faces several issues, such as those associated with the endocardial screw tip, which may cause myocardial degeneration, and the metal le

The implantable cardioverter-defibrillator (ICD) is an effective method to prevent sudden cardiac death in high-risk patients. However, the transvenous lead is incompatible with large-area electrophysiological mapping and cannot accommodate selective multichannel precision stimulations. Moreover, it involves high-energy shocks, resulting in pain, myocardial damage, and recurrences of ventricular tachyarrhythmia (VTA). We present a method for VTA treatment based on subthreshold electrical stimula

Interfaces between implantable bioelectrodes and tissues provide critical insights into the biological and pathological conditions of targeted organs, aiding diagnosis and treatment. While conventional bioelectronics, made from rigid materials like metals and silicon, have been essential for recording signals and delivering electric stimulation, they face limitations due to the mechanical mismatch between rigid devices and soft tissues. Recently, focus has shifted toward soft conductive material

Soft implantable multichannel cardiac electrode arrays that establish direct monolithic interfaces with the heart are key components for advanced cardiac monitoring and electrical modulation. A significant technological advancement in this area is the development of stretchable conductive nanocomposites, fabricated through the integration of metallic nanomaterials and elastic polymers, aimed at achieving both high electrical conductivity and mechanical elasticity. Despite these advances, further

Abstract Implantable biosensors play a critical role in healthcare and medical research by enabling real‐time monitoring of physiological signals with high precion. Compared to non‐invasive biosensors, implantable biosensors offer superior fidelity by minimizing external noise and ensuring direct contact with target tissues. However, conventional implantable biosensors, often composed of intrinsically rigid materials such as silicon and metals, suffer from mechanical mismatches with soft biologi

Abstract Flexible electronics have significantly influenced modern daily life, particularly in personalized, human-centric applications, due to their ability to conform to curved surfaces. Building on this adaptability, researchers are now focusing on developing stretchable electronic devices that promise next-generation form factors, offering unprecedented user experience and functionalities. Current approaches employ rigid electronic materials configured in strain-accommodating geometries, ach

In article number 1900768, Seung-Pyo Lee, Taeghwan Hyeon, Dae-Hyeong Kim and co-workers present a stretchable low-impedance nanocomposite comprised of Ag-Au core-shell nanowires and Pt black. The nanocomposite shows high biocompatibility and low impedance while maintaining high stretchability and conductivity. The epicardial mesh electronics made of the nanocomposite could record high-quality electrocardiograms on living animals. Moreover, global biventricular stimulation on the abnormal heart c