Sung‐Ji Park
성균관대학교 의과대학 · 의학
Sung-Ji Park 교수의 연구실은 심장질환의 조기 진단 및 위험 예측에 초점을 맞추고 있으며, 특히 심부전, 대동맥판막질환, 고혈압성 임신합병증 등에서의 영상유도 생리학적 평가와 생존 예후를 분석합니다. 심장초음파, 심장磁共振(MRI), 뇌뉴로피플로피틴(NT-proBNP) 등 다양한 영상 및 생체마커를 활용한 정밀의료 전략을 개발하고 있습니다. 특히 비심장수술 환자에서의 심혈관계 합병증 예측 및 대동맥판막질환 환자의 수술 시기 결정에 기여하는 연구가 두드러집니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
TTE was modestly predictive of perioperative cardiovascular events but was not superior to NT-proBNP. Moreover, it did not have incremental value to the clinically determined risk. The results of our study did not support the use of routine echocardiography before noncardiac surgery.
URL: https://www.clinicaltrials.gov; Unique identifier: NCT04231331.
Although CR is best related to baseline resting LVESDI, one-third of patients were found to have discordance between the presence of CR and the LV dimension recommended for aortic valve replacement (AVR) in minimally symptomatic patients with severe AR, suggesting that exercise test may be able to further stratify the current guideline for AVR.
These findings demonstrate the usefulness of CMR for early detection of subclinical LV structural and functional deterioration in AS patients.
E/e' ratio is a useful independent prognostic parameter for predicting mortality in patients with AF with preserved LV systolic function.
Background and Objectives: The role of preoperative transthoracic echocardiography (TTE) for the risk stratification has not been well investigated yet. We compared the predictive power of TTE with N-terminal pro-brain natriuretic peptide (NT-proBNP), a representative biomarker that predicts perioperative cardiovascular risk, and investigated whether these tests have incremental value to the clinically determined risk. Subjects and Methods: We evaluated the Revised Cardiac Risk Index (RCRI), TTE
To recognize MH, it is practical to investigate those patients who are taking multiple antihypertensive drugs and have a high OBP with a high FBG level. The term "ME" identifies MH more appropriately than the term "negative white-coat effect".
The concentration of betaARK1 in lymphocytes is greater in hypertensive individuals with LVH than in those without LVH and parallels the degree of hypertrophy. Generalized alterations in beta-adrenergic signalling, including betaARK1, could be a major contributory factor in the development of LVH in hypertension, and the concentration of betaARK1 in lymphocytes can reflect the development of LVH in a patient with hypertension.
RT3DE and 2D MSTE can be used to identify subtle contractile dysfunction triggered by increased LV wall thickness in severe AS with normal LVEF. Therefore, RT3D STE and 2D MSTE may provide additional information that can facilitate decision-making regarding severe AS patients with increased LV wall thickness and normal LV function.
Aortic stenosis is the most common type of valvular heart disease. Aortic stenosis is characterized both by progressive valve narrowing and the left ventricular remodeling response that ensues. In aortic stenosis, therapeutic decision essentially depends on symptomatic status, stenosis severity, and status of left ventricular systolic function. Imaging is fundamental for the initial diagnostic work-up, follow-up, and selection of the optimal timing and type of intervention. Noninvasive imaging h