Sungyoung Choi
한양대학교 전기생체공학부 · 공학
Sungyoung Choi 교수의 연구실은 주로 미세유체장치 기반의 생체입자 분리 및 집중 기술을 핵심으로 하며, 전기적 및 유체역학적 원리를 활용한 비침습적, 저손상 세포 및 입자 분리 기법을 개발하고 있습니다. 특히 유포어티크( hydrophoresis ) 기반의 입자 분리 원리를 응용해, 세포의 크기 및 물리적 특성에 기반한 정밀 분리와 혈소판, 백혈구, 혈액세포 등의 고순도 분離를 실현하고 있습니다. 연구는 의료 진단, 세포 주기 분석, 혈액제제 제조 등 임상적 응용을 목표로 하며, 고속·고순도·저스트레스 분리 기술의 실현에 초점을 맞추고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
This communication presents a microfluidic method for size-based cell sorting, which provides a simple and robust approach for cell cycle synchronization by manual and stand-alone operation.
Three-dimensional (3D) measurement of the behavior of microfluidic particles is vital for improving their operational efficiency and characterization. In particular, it is important to measure particle motions in 3D for exact characterization of hydrophoresis, which utilizes 3D convective flows for size separation. Herein, the 3D measurement of hydrophoretic particle ordering for the exact characterization of hydrophoresis by using an optically coated mirror-embedded microchannel is reported. Th
A smart multi-pipette for hand-held operation of microfluidic devices is presented and applied to cytotoxicity assays and micro-droplet generation. This method enables a continuous-flow and accurate pumping simply by pushing the plunger of the smart multi-pipette, thereby obviating the need for auxiliary equipment and special expertise in microfluidics. We applied the smart multi-pipette to a cytotoxicity assay using a gradient-generating device and water droplet generation using a T-junction de
Miniaturizing flow cytometry requires a comprehensive approach to redesigning the conventional fluidic and optical systems to have a small footprint and simple usage and to enable rapid cell analysis. Microfluidic methods have addressed some challenges in limiting the realization of microflow cytometry, but most microfluidics-based flow cytometry techniques still rely on bulky equipment (e.g., high-precision syringe pumps and bench-top microscopes). Here, we describe a comprehensive approach tha
Simple and low-cost implementation of three-dimensional (3D) particle measurement is vital for designing and characterizing microfluidic devices that show spatiotemporally varying characteristics in three dimensions. However, the conventional 3D particle image velocimetry or particle streak velocimetry has proven difficult to address the needs, requiring complex and expensive equipment, precise alignment between optical components, and specialized image-processing algorithms. Here, we report mir
