Tae‐im Kim
연세대학교 의과대학 · 의학
Tae-im Kim 교수의 연구실은 망막 혈관질환과 안과 수술 후 합병증, 특히 조기 출생 아기의 망막병변(ROP)과 레이저 안과 수술, 프라카마이드 수술 후 섬유화, 각막 상피 재생 등에 중점을 두고 있다. 특히 비만, 혈관생성 억제제의 영향, 미세한 각막 구조 변화 등 다양한 생리적·병리적 요인의 영향을 분석하며, 시력 향상과 합병증 예방을 위한 맞춤형 치료 전략 개발에 기여하고 있다. 연구는 임상 데이터 분석, 세포배양 실험, 새로운 측정 기술의 응용을 융합하여 진행된다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
To investigate the postnatal risk factors of retinopathy of prematurity (ROP), we analysed demographic and clinical data abstracted from the medical records of 425 premature babies who were examined for ROP between January 1994 and December 1998 at Asan Medical Centre, Seoul, Korea. ROP developed in 20.7% of the cases studied. A gestational age (GA) of < or = 28 weeks and birthweight (BW) of < or = 1000 g were the most significant risk factors. Ventilator care for > or = 48 h, apnoea, and use of
Wavefront-guided customized ablation reduced the increase of high order aberrations resulting from LASIK. In terms of visual acuity, patient preference, and mesopic contrast sensitivity, wavefront-guided customized ablation produced slightly-but not statistically significant-better results.
MMC is a potent inhibitor of corneal haze induced by PRK. MMC reduced the number of keratocytes and fibroblasts after PRK and UV-B irradiation. Although MMC would improve the clinical results of PRK, it has significant toxicity on corneal keratocytes, which did not disappear until 3 months after PRK.
Mitomycin C induced apoptosis, not necrosis, in cultured corneal keratocytes through the caspase pathway-specifically, caspase-8 and -9-related to the mitochondrial pathway.
Lipid layer thickness measurements using a new interferometer are significantly affected by demographic factors such as age, sex, ocular surgical history, and MGD type. Therefore, all of these factors must be considered in the diagnosis of ocular surface diseases.
Bevacizumab delayed corneal epithelial wound healing and inhibited integrin expression. When bevacizumab is used to reduce the development of new corneal vessels, slight delays in epithelial wound healing are possible and cellular proliferation is to be expected.
