The University of Osaka · 공학
이 교수의 연구실은 첨자제조 기술, 특히 선택적 레이저 용융(SLM)을 활용한 고성능 생체 금속 재료의 개발에 중점을 두고 있습니다. 저탄성 모듈러스를 가진 티타늄 기반 합금과 고엔트로피 생체합금(BioHEA)을 통해 임플란트의 생체적합성과 기계적 기능을 동시에 향상시키는 데 성공했으며, 조직 공학적 응용을 위한 생체모방적 재료 설계도 진행 중입니다. 특히 결정학적 텍스처 제어와 원자적 분포 제어를 통해 생체재료의 기계적 성능과 생체 반응성을 정밀하게 조작하는 데 핵심 기여를 하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
We first successfully achieved the two types of distinct texture control in low-modulus beta-type Ti–15Mo–5Zr–3Al alloy products using selective laser melting. Bidirectional scanning with and without a rotation of 90° between the layers gave rise to different textures with preferential orientations of 〈001〉 and 〈011〉 along the building direction, respectively. Control of the growth behavior of the columnar cells in the melt pools via scanning strategies enabled the generation of such different t
BioHEAs, specifically designed high entropy alloy (HEA) systems for biomedical applications, represent a new era for biometals. However, recent challenges are (1) the poor shape customizability, and (2) the inevitable severe segregation due to the intrinsic fact that HEA is an ultra-multicomponent alloy system. To achieve shape customization and suppression of elemental segregation simultaneously, we used an extremely high cooling rate (~107 K/s) of the selective laser melting (SLM) process. We,
The aim of the present study was to assess the bone regeneration process in defects introduced into rabbit long bones, which were regenerated with controlled release of recombinant bone morphogenetic protein-2 (rBMP-2). The orientation of the biological apatite (BAp) c-axis and bone mineral density (BMD) were compared as predictors of bone mechanical function. A 20-mm-long defect was introduced in rabbit ulnas, and 17 µg of rBMP-2 was controlled-released into the defect using a biodegradable gel
In recent years, additive manufacturing has attracted attention as a technology that enables control of the crystallographic texture of metallic materials. We achieved successful control of the crystallographic texture of 316L austenitic stainless steel using selective laser melting (SLM). Three distinguished textures were achieved by changing the laser scan speed, namely: the single crystalline-like texture with {001} orientation in the build direction, the crystallographic lamellar texture in
In metal additive manufacturing, crystallographic orientation control is a promising method for tailoring the functions of metallic parts. However, despite its importance in the fabrication of texture-controlled functional parts, the stability of the crystallographic texture is not widely discussed. Herein, the crystallographic texture stability under laser powder bed fusion was investigated. Two methodologies were employed. One is that a laser scanning strategy was alternately changed for a spe
Osteopetrotic bone shows dissociation between bone mineral density (BMD) and bone strength. In this study, volumetric BMD; preferential orientation of the extracellular matrix (ECM), which is composed of collagen fibers and apatite crystals as bone material quality; and mechanical properties of the src<sup>-/-</sup> osteopetrotic and normal mouse femoral cortical bone were analyzed and compared with each other at a bone tissue level. The degree of preferential orientation of ECM along the femora
Osteocytes are believed to play a crucial role in mechanosensation and mechanotransduction which are important for maintenance of mechanical integrity of bone. Recent investigations have revealed that the preferential orientation of bone extracellular matrix (ECM) mainly composed of collagen fibers and apatite crystallites is one of the important determinants of bone mechanical integrity. However, the relationship between osteocytes and ECM orientation remains unclear. In this study, the associa
